Reiher J, Beaudry M, Leduc C P
Department of Neurology, University of Sherbrooke, School of Medicine, Quebec, Canada.
Can J Neurol Sci. 1989 Nov;16(4):398-401. doi: 10.1017/s0317167100029450.
Temporal interictal rhythmic delta activity or TIRDA was found in 45 of the 127 recordings of patients with complex partial epilepsy (CPE) referred for both awake and sleep EEG. TIRDA was more abundant during drowsiness and light sleep; it occurred more characteristically as trains of 50-100 microv sinusoidal or saw-toothed 1-4Hz activity, recorded predominantly from anterior temporal regions. When occurring bilaterally and independently, TIRDA varied from side to side. TIRDA is often found in association with anterior temporal spikes or sharp waves (TS) particularly during sleep, as observed in 43 out of 45 EEGs. TIRDA can nevertheless occur as an isolated abnormality, as noted in two sleep and 12 awake study recordings. Because of its high specificity and positive predictive value over a large range of prevalence, TIRDA should be singled out as an accurate interictal indicator of CPE. In patients with isolated TIRDA, the cost of prolonged EEG recording during sleep for the purpose of activating TS has to be weighed against the yield of eventually confirming the obvious.
在127例因清醒和睡眠脑电图检查而转诊的复杂部分性癫痫（CPE）患者的记录中，有45例发现了颞间发作性节律性δ活动（TIRDA）。TIRDA在嗜睡和浅睡眠期间更为丰富；其更典型的表现为50 - 100微伏的正弦波或锯齿状1 - 4赫兹活动序列，主要从前颞区记录到。当TIRDA双侧独立出现时，两侧会有所不同。TIRDA常与前颞棘波或尖波（TS）相关联，尤其是在睡眠期间，45份脑电图中有43份观察到这种情况。然而，TIRDA也可能作为一种孤立的异常出现，如在2份睡眠记录和12份清醒研究记录中所发现的。由于TIRDA在广泛的患病率范围内具有高特异性和阳性预测价值，它应被视为CPE准确的发作间期指标。对于孤立性TIRDA患者，为激活TS而在睡眠期间延长脑电图记录的成本，必须与最终确认明显症状的收益相权衡。
