Shin Jae Jun, Jee Byung Chul, Kim Hoon, Kim Seok Hyun
Department of Obstetrics and Gynecology, Seoul National University Bundang Hospital, Seongnam, Korea.
Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Korea.
J Korean Med Sci. 2017 Feb;32(2):321-328. doi: 10.3346/jkms.2017.32.2.321.
We investigated the prevalence of smoking and factors associated with smoking in infertile Korean women. Smoking status, education, occupation, personal habits, past medical history, current illness, stress level, and menstrual characteristics were collected from self-report questionnaires. The Beck Depression Inventory (BDI) was used to assess the degree of depression. Data on the causes of infertility and levels of six reproductive hormones were collected from medical records. Among 785 women less than 42 years of age, the prevalence of current, secondhand, past, and never smokers were 12.7%, 45.7%, 0.9%, and 40.6%, respectively. Primary infertility was more frequent in secondhand smokers. Causes of infertility were similar among current, secondhand, and never smokers. Current smokers were less educated (P < 0.001) and more likely to consume alcohol than secondhand or never smokers (P < 0.001). Secondhand smokers slept less than current smokers (P = 0.041). Among several major diseases, only the prevalence of diabetes mellitus (4.0%) was significantly higher in current smokers than in secondhand smokers (0.0%, P = 0.002) or never smokers (0.6%, P = 0.031). The self-reported prevalence of depression, and the degree of depression were similar among women with different smoking statuses. There were no differences in menstrual characteristics or serum levels of six reproductive hormones between current, secondhand, and never smokers, even after excluding women with polycystic ovary syndrome. In conclusion, education/employment status, alcohol drinking, and the prevalence of primary infertility and diabetes mellitus were significantly different according to smoking status among infertile women.
我们调查了韩国不孕女性的吸烟率及与吸烟相关的因素。通过自填问卷收集吸烟状况、教育程度、职业、个人习惯、既往病史、当前疾病、压力水平和月经特征等信息。使用贝克抑郁量表（BDI）评估抑郁程度。从病历中收集不孕原因及六种生殖激素水平的数据。在785名42岁以下的女性中，当前吸烟者、二手烟暴露者、既往吸烟者和从不吸烟者的比例分别为12.7%、45.7%、0.9%和40.6%。二手烟暴露者原发性不孕更为常见。当前吸烟者、二手烟暴露者和从不吸烟者的不孕原因相似。当前吸烟者受教育程度较低（P < 0.001），且比二手烟暴露者或从不吸烟者更有可能饮酒（P < 0.001）。二手烟暴露者的睡眠时间比当前吸烟者少（P = 0.041）。在几种主要疾病中，仅糖尿病的患病率（4.0%）在当前吸烟者中显著高于二手烟暴露者（0.0%，P = 0.002）或从不吸烟者（0.6%，P = 0.031）。不同吸烟状况女性的抑郁自评患病率及抑郁程度相似。即使排除多囊卵巢综合征患者，当前吸烟者、二手烟暴露者和从不吸烟者在月经特征或六种生殖激素的血清水平方面也没有差异。总之，不孕女性的教育/就业状况、饮酒情况以及原发性不孕和糖尿病的患病率根据吸烟状况存在显著差异。
