Shimazaki Yoshihiro, Fu Bohan, Yonemoto Koji, Akifusa Sumio, Shibata Yukie, Takeshita Toru, Ninomiya Toshiharu, Kiyohara Yutaka, Yamashita Yoshihisa
Section of Preventive and Public Health Dentistry, Division of Oral Health, Growth and Development, Faculty of Dental Science, Kyushu University.
J Oral Sci. 2017 Mar 31;59(1):55-62. doi: 10.2334/josnusd.16-0372. Epub 2016 Dec 28.
This study examined the relationship between stimulated salivary flow rate and oral health status in an adult population. Multinomial multivariate logistic regression analysis was used to examine the associations of salivary flow rate with dental caries status and periodontal status at the individual level among 2,110 Japanese adults with ≥10 teeth. Then, a spline model was used to examine the nonlinear relationship between salivary flow rate and teeth with dental caries or periodontal disease in multilevel analysis. Odds ratios were calculated for a 1.0-mL/min reduction in salivary flow rate at a point. After adjusting for confounding variables, participants with a flow rate ≤3.5 mL/min had significantly higher odds ratios for high caries status, and participants with a flow rate ≤1.4 mL/min had a higher odds ratio for broad periodontal disease, than did those with a flow rate >3.5 mL/min. In spline models, the odds ratio for teeth with dental caries or periodontal disease increased with reduced saliva secretion. The present findings suggest that decreased saliva secretion affects both dental caries and general periodontal health status.
本研究调查了成年人群中刺激唾液流速与口腔健康状况之间的关系。采用多项多变量逻辑回归分析,在2110名牙齿数≥10颗的日本成年人个体水平上,研究唾液流速与龋齿状况和牙周状况之间的关联。然后,在多水平分析中使用样条模型研究唾液流速与患龋齿或牙周疾病牙齿之间的非线性关系。计算了唾液流速在某一点降低1.0 mL/分钟时的比值比。在调整混杂变量后,唾液流速≤3.5 mL/分钟的参与者患高龋齿状况的比值比显著更高,唾液流速≤1.4 mL/分钟的参与者患广泛牙周疾病的比值比高于唾液流速>3.5 mL/分钟的参与者。在样条模型中,患龋齿或牙周疾病牙齿的比值比随着唾液分泌减少而增加。目前的研究结果表明,唾液分泌减少会影响龋齿和总体牙周健康状况。