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欧司通MasterPlan治疗计划系统近距离治疗模块的调试

Commissioning of brachytherapy module of Oncentra MasterPlan treatment planning system.

作者信息

de Oliveira Carla Alves, Lopes Maria do Carmo, Matos Armanda

机构信息

Instituto Português de Oncologia de Coimbra Francisco Gentil, EPE, Coimbra, Portugal.

出版信息

J Contemp Brachytherapy. 2009 Dec;1(4):224-230. Epub 2010 Jan 13.

Abstract

PURPOSE

To describe the tests that have been performed in order to commission the Brachytherapy module, version 3.2, service pack 3.0, of the Oncentra MasterPlan treatment plan system (OB), from Nucletron. The results were benchmarked against those obtained with the Plato system, v 14.3.7, also from Nucletron, used in the clinical routine.

MATERIAL AND METHODS

Commissioning was performed taking Plato, v 14.3.7 as the standard TPS used in clinical practice. Commissioning tests were divided into two categories: i) simple geometric catheter configurations and ii) clinical intracavitary gynaecological and interstitial breast implants. For category i), also manual independent point dose calculations following the TG-43 dosimetry protocol were included in the comparisons. For category ii), the treatment plan comparisons were based on the calculated dose distributions in CT axial plans and on the dose-volume quality indexes following the local clinical acceptance criteria. Similar optimization tools were used in both systems. IPSA in OB was tested for planning interstitial breast implants and compared with the optimization process used with Plato in the clinical routine.

RESULTS AND CONCLUSIONS

Regarding the point dose calculations, the agreement was better than 1%. For the clinical compared cases and using the same optimization tools all plans ended in similar dose distributions and very close quality indexes. Nevertheless, for endovaginal treatment plans, a slightly different value for the DTGR parameter had to be used (0.452, instead of 0.5 used as default in PLATO) in order to achieve the same dwell time for each activated source dwell position. Concerning interstitial breast implants, the IPSA algorithm constitutes a fast tool to reach a close clinical acceptable solution but Graphical Optimization is still needed. Considering these results the OB module was accepted for clinical use despite some persisting limitations, such as no consideration of heterogeneities or options for applicator shielding.

摘要

目的

描述为启用核通公司Oncentra MasterPlan治疗计划系统(OB)的近距离治疗模块3.2版、服务包3.0版所进行的测试。将结果与临床常规使用的核通公司的Plato系统v 14.3.7所获得的结果进行基准对比。

材料与方法

以临床实践中使用的Plato v 14.3.7作为标准治疗计划系统进行启用测试。启用测试分为两类:i)简单几何形状的导管配置,ii)临床腔内妇科和间质乳腺植入。对于i类,比较中还包括按照TG - 43剂量测定协议进行的手动独立点剂量计算。对于ii类,治疗计划比较基于CT轴向平面中的计算剂量分布以及遵循当地临床验收标准的剂量 - 体积质量指标。两个系统都使用了类似的优化工具。对OB中的IPSA进行了间质乳腺植入规划测试,并与临床常规中使用Plato的优化过程进行了比较。

结果与结论

关于点剂量计算,一致性优于1%。对于临床比较的病例,使用相同的优化工具,所有计划的剂量分布相似,质量指标非常接近。然而,对于阴道内治疗计划,为了使每个激活源驻留位置的驻留时间相同,必须使用略不同的DTGR参数值(0.452,而不是Plato中默认使用的0.5)。关于间质乳腺植入,IPSA算法是一种快速工具,可得出接近临床可接受的解决方案,但仍需要图形优化。考虑到这些结果,尽管存在一些持续的限制,如未考虑不均匀性或施源器屏蔽选项,OB模块仍被接受用于临床。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e28a/5086490/a44e3e27e592/JCB-1-14044-g001.jpg

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