Capelli Marco, Gatti Patrizia
Doctor, ENT Casa di Cura "Lecco" , Lecco, Italy .
J Clin Diagn Res. 2016 Nov;10(11):MC07-MC10. doi: 10.7860/JCDR/2016/22365.8931. Epub 2016 Nov 1.
Inflammatory diseases of the maxillary sinus favour the thickening of the sinus mucosa. Therefore, it might be possible to establish a radiological, pathological threshold of mucosal thickening. Furthermore, there is an association between common anatomic variants of the nose and maxillary mucosal thickening.
To define the pathological thickening of maxillary sinus mucosa and its association with the presence of common anatomic variants (concha bullosa, Haller's cell and accessory maxillary ostium).
From March 2014 to February 2016, Two hundred patients underwent Cone Beam Computed Tomography (CBCT) of the paranasal sinus. We conducted this retrospective study of total 70 patients, 34 patients i.e., a total of 68 meatus-maxillary units (study group - those affected by Chronic Rhinosinusitis (CRS) and another 36 patients i.e., a total of 72 meatus maxillary units (control group - without symptoms of CRS). We assessed the degree of thickening of the sinus mucosa distinguishing between ≥ 2mm or ≤ 2mm, than we analysed the behaviour of the thickness in the study group and in the control group. Chi-Square test was used to compare mucosal thickening between study and control group and the presence of some common anatomic variants or closure of maxillary ostium.
In the study group we observed a clear association between maxillary mucosal thickening ≥ 2mm and CRS (p<0.01). We however, observed no association between the presence of common anatomic variations and thickening of the maxillary mucosa and between the presence of common anatomic variations and the study group. Instead, using a binary logistic regression, we observed a significant association (p<0.01) between closure of natural ostium of the maxillary sinus and mucosal thickening or between closure of natural ostium and study group.
We believe that a thickening of the maxillary mucosa ≥ 2mm and closure of natural maxillary ostium are statistically associated with CRS. The common anatomical variants do not seem to be associated with this condition.
上颌窦炎性疾病易导致窦黏膜增厚。因此，有可能建立一个关于黏膜增厚的放射学、病理学阈值。此外，鼻腔常见解剖变异与上颌窦黏膜增厚之间存在关联。
明确上颌窦黏膜的病理性增厚及其与常见解剖变异（泡性鼻甲、哈勒氏气房和上颌窦副口）的存在之间的关联。
2014年3月至2016年2月，200例患者接受了鼻窦锥形束计算机断层扫描（CBCT）。我们对总共70例患者进行了这项回顾性研究，其中34例患者，即总共68个鼻道 - 上颌窦单位（研究组 - 患有慢性鼻 - 鼻窦炎（CRS）），另外36例患者，即总共72个鼻道 - 上颌窦单位（对照组 - 无CRS症状）。我们评估了窦黏膜增厚程度，区分≥2mm或≤2mm，然后分析了研究组和对照组中厚度的表现。采用卡方检验比较研究组和对照组之间的黏膜增厚情况以及一些常见解剖变异或上颌窦口闭合的情况。
在研究组中，我们观察到上颌窦黏膜增厚≥2mm与CRS之间存在明显关联（p<0.01）。然而，我们未观察到常见解剖变异的存在与上颌窦黏膜增厚之间以及常见解剖变异的存在与研究组之间存在关联。相反，使用二元逻辑回归，我们观察到上颌窦自然口闭合与黏膜增厚之间或自然口闭合与研究组之间存在显著关联（p<0.01）。
我们认为上颌窦黏膜增厚≥2mm和上颌窦自然口闭合与CRS在统计学上相关。常见解剖变异似乎与这种情况无关。
