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从传统用途到药理学证据:对L.的系统评价

From Traditional Usage to Pharmacological Evidence: Systematic Review of L.

作者信息

Maroyi Alfred

机构信息

Department of Botany, University of Fort Hare, Private Bag X1314, Alice 5700, South Africa.

出版信息

Evid Based Complement Alternat Med. 2016;2016:1720123. doi: 10.1155/2016/1720123. Epub 2016 Dec 7.

Abstract

is the only species of the genus that has been recorded in Africa. Its leaves, rhizomes, roots, and stems are reported to possess diverse medicinal properties and used to treat or manage various human and animal diseases and ailments. is an ingredient in many herbal concoctions and prescriptions which have been used to induce or augment labour, postnatal medication, to treat parasitic diseases, urinary complaints, kidney problems, general body pains, sexually transmitted infections, and many other diseases. Several classes of phytochemicals including alkaloids, benzoquinones, ellagic acids, flavonoids, phenols, proanthocyanidins, tannins, and minerals have been isolated from . Scientific studies on indicate that it has a wide range of pharmacological activities including acetylcholinesterase, anthelmintic, antibacterial, antifungal, antinociceptive, anti-inflammatory, antioxidant, antitumour, lactogenic, and uterotonic. has a lot of potential as a possible source of pharmaceutical products for the treatment of a wide range of both human and animal diseases and ailments. Some of the chemical compounds isolated from have demonstrated various biological activities when investigated in assays. Future research should focus on the mechanisms of action of the isolated compounds, their efficacy, toxicity, and clinical relevance.

摘要

是该属中唯一在非洲有记录的物种。据报道,其叶、根茎、根和茎具有多种药用特性,可用于治疗或管理各种人类和动物疾病及病痛。是许多草药配方和方剂中的一种成分,这些配方和方剂已被用于引产或增强宫缩、产后用药、治疗寄生虫病、泌尿系统疾病、肾脏问题、全身疼痛、性传播感染以及许多其他疾病。已从该植物中分离出几类植物化学物质,包括生物碱、苯醌、鞣花酸、黄酮类化合物、酚类、原花青素、单宁和矿物质。对该植物的科学研究表明,它具有广泛的药理活性,包括乙酰胆碱酯酶抑制、驱虫、抗菌、抗真菌、抗伤害感受、抗炎、抗氧化、抗肿瘤、催乳和子宫收缩作用。作为治疗广泛的人类和动物疾病及病痛的药品潜在来源,该植物具有很大潜力。从该植物中分离出的一些化合物在实验研究中已显示出各种生物活性。未来的研究应集中在分离出的化合物的作用机制、疗效、毒性和临床相关性上。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d112/5174174/14205e9bad55/ECAM2016-1720123.001.jpg

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