Łukomska-Szymańska Monika, Zarzycka Beata, Grzegorczyk Janina, Sokołowski Krzysztof, Półtorak Konrad, Sokołowski Jerzy, Łapińska Barbara
Department of General Dentistry, Medical University of Lodz, Lodz, Poland.
Department of Microbiology and Laboratory Medical Immunology, Medical University of Lodz, Lodz, Poland.
Biomed Res Int. 2016;2016:1048320. doi: 10.1155/2016/1048320. Epub 2016 Dec 8.
The aim of the study was to evaluate antibacterial activity of composite materials modified with calcium fluoride against cariogenic bacteria and . One commercially available conventional light-curing composite material containing fluoride ions (F2) and two commercially available flowable light-curing composite materials (Flow Art and X-Flow) modified with 1.5, 2.5, and 5.0 wt% anhydrous calcium fluoride addition were used in the study. Composite material samples were incubated in 0.95% NaCl at 35°C for 3 days; then dilution series of and strains were made from the eluates. Bacteria dilutions were cultivated on media afterwards. Colony-forming unit per 1 mL of solution (CFU/mL) was calculated. Composite materials modified with calcium fluoride highly reduced ( < 0.001) bacteria growth compared to commercially available composite materials containing fluoride compounds. The greatest reduction in bacteria growth was observed for composite materials modified with 1.5% wt. CaF. All three tested composite materials showed statistically greater antibacterial activity against than against .
该研究的目的是评估用氟化钙改性的复合材料对致龋菌的抗菌活性。研究中使用了一种市售的含氟离子的传统光固化复合材料（F2）以及两种分别添加了1.5%、2.5%和5.0 wt%无水氟化钙改性的市售可流动光固化复合材料（Flow Art和X-Flow）。将复合材料样品在35°C的0.95% NaCl中孵育3天；然后从洗脱液中制备变形链球菌和远缘链球菌的稀释系列。之后将细菌稀释液接种在培养基上培养。计算每1 mL溶液中的菌落形成单位（CFU/mL）。与市售含氟化合物的复合材料相比，用氟化钙改性的复合材料能显著降低（P < 0.001）细菌生长。观察到添加1.5% wt. CaF2改性的复合材料对细菌生长的抑制作用最大。所有三种测试的复合材料对变形链球菌的抗菌活性在统计学上均高于对远缘链球菌的抗菌活性。
