Stewart Catherine S, McEwen Fiona S, Konstantellou Anna, Eisler Ivan, Simic Mima
National and Specialist Child and Adolescent Eating Disorder Service, South London and Maudsley NHS Foundation Trust, London, UK.
Child and Adolescent Psychiatry and Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Eur Eat Disord Rev. 2017 Mar;25(2):123-128. doi: 10.1002/erv.2497. Epub 2017 Jan 6.
Evidence links high levels of Autism Spectrum Disorder Traits in women with chronicity of anorexia nervosa. This study reports through clinical audit the impact of ASD traits on treatment outcomes of girls who were referred for treatment in a specialist eating disorder service. Presence of current, but not early childhood, ASD traits was elevated in comparison with previously reported community samples. Current ASD traits were correlated with emotional disorders and with need for treatment augmentation (psychiatric inpatient or day patient admission), but this relationship was not significant after the contribution of depression had been controlled for. There was no difference in Morgan Russell Outcomes at discharge for those with high and low current ASD traits. Parent-reported ASD-related developmental difficulties were associated with attenuated change in self-reported cognitive symptoms of AN. This study highlights the need for further understanding of the aetiology, diagnostic significance and predictive utility for future relapse of elevated ASD traits in childhood eating disorders. Copyright © 2017 John Wiley & Sons, Ltd and Eating Disorders Association.
有证据表明，患有神经性厌食症慢性病的女性具有高水平的自闭症谱系障碍特征。本研究通过临床审计报告了自闭症谱系障碍特征对在专业饮食失调服务机构接受治疗的女孩治疗结果的影响。与先前报告的社区样本相比，当前（而非幼儿期）自闭症谱系障碍特征的发生率有所升高。当前的自闭症谱系障碍特征与情绪障碍以及强化治疗需求（精神科住院或日间住院）相关，但在控制了抑郁症的影响后，这种关系并不显著。当前自闭症谱系障碍特征高和低的患者出院时的摩根·拉塞尔结果没有差异。家长报告的与自闭症谱系障碍相关的发育困难与神经性厌食症自我报告的认知症状变化减弱有关。本研究强调需要进一步了解儿童饮食失调中自闭症谱系障碍特征升高的病因、诊断意义和对未来复发的预测效用。版权所有© 2017约翰·威利父子有限公司和饮食失调协会。
