Yu M, Zhao B X
Zhonghua Shen Jing Jing Shen Ke Za Zhi. 1989 Feb;22(1):8-11, 61.
90 cases of multiple scleroses were studied in connexion with the course and prognosis of the disease. The course of this disease may be classified into 4 type: benign, remitting progressive, and chronic progressive types. Relapse took place in 75% of the patients. The frequency of relapse was on the average 0.45 time per year. Severe disability occurred mostly during the first five years. The present study suggested that the factors indicating relatively poor prognosis would be the onset at the age over 40 years, chronic insidious onset, early severe impairment of the pyramidal tract function and multiple involvement of the different systems in the CNS.
对90例多发性硬化症患者的病程及预后进行了研究。该疾病的病程可分为4种类型：良性型、缓解进展型和慢性进展型。75%的患者出现复发。复发频率平均每年0.45次。严重残疾大多发生在最初五年。本研究表明，提示预后相对较差的因素包括40岁以上起病、慢性隐匿起病、锥体束功能早期严重受损以及中枢神经系统不同系统的多处受累。
