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[胰激肽释放酶,缺血后毒血症中小肠损伤的保护因子]

[Pancreatic kallikrein, a protector of small intestine damage in post-ischemic toxemia].

作者信息

Protsenko V A, Lutsik N G, Nesterov E N, Kharchenko V Z

出版信息

Farmakol Toksikol. 1989 Jul-Aug;52(4):34-6.

PMID:2806524
Abstract

The morphofunctional state of the small intestine was studied on a tourniquet shock model. The development of postischemic toxemia is followed by disorders of microcirculation leading to irreversible changes in the small intestine. The processes are associated with an increase of the proteolytic activity of the intestinal contents. An oral administration of andecaline prevents ischemia of the intestine, contributes to the preservation of its mucosa.

摘要

在止血带休克模型上研究了小肠的形态功能状态。缺血后毒血症的发展伴随着微循环紊乱,导致小肠发生不可逆变化。这些过程与肠内容物蛋白水解活性的增加有关。口服安替卡林可预防肠道缺血,有助于保护其黏膜。

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