Baltzer J, Kürzl R, Schramm T, Land W, Landgraf R, Eigler J, Gurland H J, Kuhlmann H, Lipowsky G
I. Frauenklinik der Universität München.
Geburtshilfe Frauenheilkd. 1989 Sep;49(9):769-75. doi: 10.1055/s-2008-1036083.
Uraemic patients are in general infertile. Ovarian function is, however, restored after successful renal transplantation, thus making conception possible. We followed up 14 patients after renal transplantation involving 16 pregnancies. Two patients became pregnant twice, one with twins and the other following renal and pancreatic transplantation--the first recorded in the world. Caesarean section was performed in all patients due to increasing serum creatinin levels, avoid pre-eclampsia or premature rupture of membranes. Both, mother and child in all cases progressed without complications, although these pregnancies are associated with high risk for both. Therefore, a close co-operation between the mother, the nephrologist, the transplantation centre, the gynaecologist and the paediatrician is a prerequisite for a possible favourable course.
尿毒症患者通常不育。然而，肾移植成功后卵巢功能会恢复，从而使受孕成为可能。我们对14例肾移植患者进行了随访，共发生16次妊娠。2例患者怀孕两次，其中1例怀的是双胞胎，另1例是在肾和胰腺联合移植后怀孕——这是世界上首例有记录的此类情况。由于血清肌酐水平升高、为避免先兆子痫或胎膜早破，所有患者均行剖宫产。尽管这些妊娠对母婴双方都有高风险，但所有病例中的母婴均顺利进展，无并发症发生。因此，母亲、肾病科医生、移植中心、妇科医生和儿科医生之间密切合作是取得良好预后的前提条件。
