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颞下颌关节紊乱病:旧观念与新概念

Temporomandibular disorders: Old ideas and new concepts.

作者信息

List Thomas, Jensen Rigmor Højland

机构信息

1 Department of Orofacial Pain and Jaw Function, Faculty of Odontology, Malmö University, Malmö, Sweden.

2 Scandinavian Center for Orofacial Neurosciences (SCON), Malmö, Sweden.

出版信息

Cephalalgia. 2017 Jun;37(7):692-704. doi: 10.1177/0333102416686302. Epub 2017 Jan 9.

Abstract

Background Temporomandibular disorders (TMD) is an umbrella term for pain and dysfunction involving the masticatory muscles and the temporomandibular joints (TMJs). TMD is the most common orofacial pain condition. Its prominent features include regional pain in the face and preauricular area, limitations in jaw movement, and noise from the TMJs during jaw movements. TMD affects up to 15% of adults and 7% of adolescents. Chronic pain is the overwhelming reason that patients with TMD seek treatment. TMD can associate with impaired general health, depression, and other psychological disabilities, and may affect the quality of life of the patient. Assessment Evaluations indicate that the recently published Diagnostic Criteria for TMD (DC/TMD) are reliable and valid. These criteria cover the most common types of TMD, which include pain-related disorders (e.g., myalgia, headache attributable to TMD, and arthralgia) as well as disorders associated with the TMJ (primarily disc displacements and degenerative disease). As peripheral mechanisms most likely play a role in the onset of TMD, a detailed muscle examination is recommended. The persistence of pain involves more central factors, such as sensitization of the supraspinal neurons and second-order neurons at the level of the spinal dorsal horn/trigeminal nucleus, imbalanced antinociceptive activity, and strong genetic predisposition, which also is included in DC/TMD. Conclusion The etiology is complex and still not clearly understood, but several biological and psychosocial risk factors for TMD have been identified. Several studies indicate that patients with TMD improve with a combination of noninvasive therapies, including behavior therapy, pharmacotherapy, physical therapy, and occlusal appliances. More stringently designed studies, however, are needed to assess treatment efficacy and how to tailor treatment to the individual patient.

摘要

背景

颞下颌关节紊乱病(TMD)是一个涵盖咀嚼肌和颞下颌关节(TMJ)疼痛及功能障碍的统称。TMD是最常见的口腔面部疼痛病症。其突出特征包括面部和耳前区域的局部疼痛、下颌运动受限以及下颌运动时TMJ发出的响声。TMD影响高达15%的成年人和7%的青少年。慢性疼痛是TMD患者寻求治疗的主要原因。TMD可能与整体健康受损、抑郁及其他心理障碍相关,且可能影响患者的生活质量。

评估

评估表明,最近发布的TMD诊断标准(DC/TMD)可靠且有效。这些标准涵盖了TMD最常见的类型,包括疼痛相关病症(如肌痛、TMD所致头痛和关节痛)以及与TMJ相关的病症(主要是盘状移位和退行性疾病)。由于外周机制很可能在TMD的发病中起作用,建议进行详细的肌肉检查。疼痛的持续存在涉及更多中枢因素,如脊髓背角/三叉神经核水平的脊髓上神经元和二级神经元的敏化、抗伤害感受活动失衡以及强烈的遗传易感性,DC/TMD中也包含这些因素。

结论

病因复杂且仍未完全明确,但已确定了TMD的一些生物和社会心理风险因素。多项研究表明,TMD患者通过行为疗法、药物疗法、物理疗法和咬合器具等非侵入性疗法的联合使用可得到改善。然而,需要更严格设计的研究来评估治疗效果以及如何根据个体患者定制治疗方案。

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