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周末急诊医疗入院的生存分析。

Survival analysis of weekend emergency medical admissions.

机构信息

From the Department of Internal Medicine, St James's Hospital, James's Street, Dublin 8, Ireland.

Department of Medical Physics and Bioengineering, St. James Hospital, James's Street, Dublin 8, Ireland.

出版信息

QJM. 2017 May 1;110(5):291-297. doi: 10.1093/qjmed/hcw219.

Abstract

BACKGROUND

We previously reported weekend emergency admissions to have a higher mortality; we have now examined the time profile of deaths, by weekday or weekend admission, in all emergency medical patients admitted between 2002 and 2014.

METHODS

We divided admissions by a weekday or weekend (After 17.00 Friday-Sunday) hospital arrival. We examined survival following an admission using Cox proportional hazard models and Kaplan-Meier time to event analysis.

RESULTS

In total 82 368 admissions were recorded in 44, 628 patients. Weekend admissions had an increased mortality of 5.0% (95% CI 4.7, 5.4) compared with weekday admissions of 4.5% (95% CI 4.3, 4.7) ( P = 0.007). The univariate adjusted Odds Ratio (OR) of death for a weekend admission was significantly increased OR = 1.15 (95% CI 1.05, 1.24) ( P = 0.001). Mortality following an admission declined exponentially over time with a long tail, ∼25% of deaths occurred after day 28. Only 11.4% of deaths occurred on the weekend of the admission. Survival curves showed no mortality difference at 28 days ( P = 0.21) but a difference at 90 days ( P = 0.05). The higher mortality for a weekend admission was attributable to late deaths in the cohort with an extended stay; compared with weekday, these weekend admissions were more likely to be older and have greater co-morbidity.

CONCLUSION

Survival rates following a weekend or weekday admission were similar out to 28 days. The higher overall mortality for weekend admissions is due to divergence in survival between 28 and 90 days. Most deaths in weekend admissions occurred when the hospital was fully staffed.

摘要

背景

我们之前报告过周末急诊入院的死亡率较高;现在我们检查了所有在 2002 年至 2014 年期间入院的急诊患者,按入院日期(周五 17 点后至周日)分析了按工作日或周末的死亡时间分布。

方法

我们将入院时间分为工作日或周末(周五 17 点后至周日)。使用 Cox 比例风险模型和 Kaplan-Meier 时间事件分析,检查入院后的生存情况。

结果

共记录了 82368 次入院,涉及 44628 名患者。与工作日入院相比,周末入院的死亡率增加了 5.0%(95%CI 4.7,5.4),而工作日入院的死亡率为 4.5%(95%CI 4.3,4.7)(P=0.007)。周末入院的死亡风险的单变量调整后的比值比(OR)显著增加,OR=1.15(95%CI 1.05,1.24)(P=0.001)。入院后死亡率随时间呈指数下降,长尾分布,约 25%的死亡发生在第 28 天之后。只有 11.4%的死亡发生在入院的周末。28 天的生存曲线无差异(P=0.21),但 90 天的差异有统计学意义(P=0.05)。周末入院死亡率较高归因于队列中延长住院时间的晚期死亡;与工作日入院相比,这些周末入院的患者年龄更大,合并症更多。

结论

周末或工作日入院后的生存率在 28 天内相似。周末入院的总体死亡率较高是由于 28 天至 90 天的生存率差异。周末入院的大多数死亡发生在医院人员配备充足时。

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