Galyfos George, Sianou Argyri, Filis Konstantinos
Department of Propaedeutic Surgery, Division of Vascular Surgery, University of Athens Medical School, Hippocration Hospital, Athens, Greece.
Department of Microbiology, University of Athens Medical School, Areteion Hospital, Athens, Greece.
Ann Card Anaesth. 2017 Jan;20(Supplement):S43-S48. doi: 10.4103/0971-9784.197796.
Statins belong to a specific group of drugs that have been described for their ability to control hyperlipidemia as well as for other pleiotropic effects such as improving vascular endothelial function, inhibition of oxidative stress pathways, and anti-inflammatory actions. Accumulating clinical evidence strongly suggests that statins also have a beneficial effect on perioperative morbidity and mortality. Therefore, this review aims to present all recent and pooled data on statin treatment in the perioperative setting as well as to highlight considerations regarding their indications and therapeutic application.
他汀类药物属于一类特定的药物，其已被描述具有控制高脂血症的能力以及其他多效性作用，如改善血管内皮功能、抑制氧化应激途径和抗炎作用。越来越多的临床证据强烈表明，他汀类药物对围手术期发病率和死亡率也有有益影响。因此，本综述旨在呈现围手术期他汀类药物治疗的所有最新和汇总数据，并强调有关其适应证和治疗应用的注意事项。
