Department of Physics, and Institute of Nanotechnology and Advanced Materials, Bar-Ilan University, Ramat Gan 52900, Israel.
Soft Matter. 2017 Feb 7;13(5):963-968. doi: 10.1039/c6sm02722a. Epub 2017 Jan 12.
We consider how active forces modeled as non-thermal random noise affect the average dynamical properties of a Rouse polymer. As the power spectrum of the noise is not known we keep the analytical treatment as generic as possible and then present results for a few examples of active noise. We discuss the connection between our results and recent experimental studies of dynamics of labeled DNA telomeres in living cells, and propose new chromatin tracking experiments that will allow one to determine the statistical properties of the active forces associated with chromatin remodeling processes.
我们研究了非热随机噪声形式的活跃力如何影响 Rouse 聚合物的平均动力学性质。由于噪声的功率谱未知,我们尽可能保持分析处理的通用性,然后给出一些活跃噪声的示例结果。我们讨论了我们的结果与最近关于活细胞中标记 DNA 端粒动力学的实验研究之间的联系,并提出了新的染色质追踪实验,这将使人们能够确定与染色质重塑过程相关的活跃力的统计性质。