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单眼与双眼融合视野对视力相关生活质量影响的比较

Comparison of Impact of Monocular and Integrated Binocular Visual Fields on Vision-related Quality of Life.

作者信息

Chun Yeoun Sook, Lee Dong Ik, Kwon Jaein, Park In Ki

机构信息

*Department of Ophthalmology, Chung-Ang University College of Medicine, Chung-Ang University Hospital ‡Department of Ophthalmology, Kyung Hee University College of Medicine, Kyung Hee University Hospital, Seoul, South Korea †Division of Biological Sciences, University of California, San Diego, CA.

出版信息

J Glaucoma. 2017 Mar;26(3):283-291. doi: 10.1097/IJG.0000000000000623.

Abstract

PURPOSE OF THE STUDY

The purpose of the study was to investigate the relationship between vision-related quality of life (VRQOL) and mean deviation (MD) of the monocular visual field and integrated binocular visual field (IBVF).

METHODS

One hundred eighty VFs (90 pairs) obtained from 90 patients with normal tension glaucoma were included. VRQOL was evaluated using the 25-item National Eye Institute Visual Function Questionnaire (NEI VFQ-25). IBVF was calculated using maximal sensitivity and binocular summation and IBVF MD was calculated. Multiple linear regression analysis was used to assess the impact of IBVF deficit on VRQOL after adjusting for confounding factors. These results were compared to those of monocular visual field.

RESULTS

Mean subject age was 59.4 years. The average MD of maximal sensitivity was significantly higher than that of binocular summation, the better eye, and the worse eye (-3.27, -3.78, -3.96, and -8.66 dB, respectively, P<0.001). Rasch-analyzed NEI VFQ-25 subscales and composite scores were significantly correlated with IBVF deficit. The impact that IBVF had on VRQOL was similar to that of the better eye (R of 0.431, 0.422, and 0.422 for MD of the better eye, binocular summation, and maximal sensitivity, respectively). In contrast, the worse eye showed the least correlation with VRQOL (0.363).

CONCLUSIONS

The impact of IBVF on VRQOL was similar to that of the better eye irrespective of integration method. Therefore, better eye MD could be a good indicator for VRQOL.

摘要

研究目的

本研究旨在探讨单眼视野和双眼综合视野(IBVF)的视力相关生活质量(VRQOL)与平均偏差(MD)之间的关系。

方法

纳入90例正常眼压性青光眼患者的180个视野(90对)。使用25项美国国立眼科研究所视觉功能问卷(NEI VFQ - 25)评估VRQOL。通过最大敏感度和双眼总和计算IBVF,并计算IBVF MD。在调整混杂因素后,采用多元线性回归分析评估IBVF缺陷对VRQOL的影响。将这些结果与单眼视野的结果进行比较。

结果

受试者平均年龄为59.4岁。最大敏感度的平均MD显著高于双眼总和、较好眼和较差眼(分别为-3.27、-3.78、-3.96和-8.66 dB,P<0.001)。经拉施分析的NEI VFQ - 25分量表和综合评分与IBVF缺陷显著相关。IBVF对VRQOL的影响与较好眼相似(较好眼、双眼总和和最大敏感度的MD的R值分别为0.431、0.422和0.422)。相比之下,较差眼与VRQOL的相关性最小(0.363)。

结论

无论整合方法如何,IBVF对VRQOL的影响与较好眼相似。因此,较好眼的MD可能是VRQOL的一个良好指标。

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