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首例与人类冠状病毒NL63感染相关的婴儿死亡病例。

The First Infant Death Associated With Human Coronavirus NL63 Infection.

作者信息

Konca Capan, Korukluoglu Gulay, Tekin Mehmet, Almis Habip, Bucak İbrahim Hakan, Uygun Hatice, Altas Ayse Basak, Bayrakdar Fatma

机构信息

From the *Department of Pediatrics, Adiyaman University, School of Medicine, Adiyaman, Turkey; and †Public Health Institutions of Turkey, National Virology Reference Laboratory/National Influenza Center, Ankara, Turkey.

出版信息

Pediatr Infect Dis J. 2017 Feb;36(2):231-233. doi: 10.1097/INF.0000000000001390.

DOI:10.1097/INF.0000000000001390
PMID:28081049
Abstract

Human coronavirus NL63 (HCoV-NL63) primarily infects the upper respiratory tract. However, it may cause severe lower respiratory tract infection, and the clinical course may be severe in immunocompromised patients. To our knowledge, child death due to HCoV-NL63 has not been reported. We present a fatal lower respiratory tract disease associated with HCoV-NL63 in a 7-month-old malnourished infant.

摘要

人冠状病毒NL63(HCoV-NL63)主要感染上呼吸道。然而,它可能导致严重的下呼吸道感染,并且在免疫功能低下的患者中临床病程可能较为严重。据我们所知,尚未有因HCoV-NL63导致儿童死亡的报道。我们报告了一例7个月大营养不良婴儿发生的与HCoV-NL63相关的致命性下呼吸道疾病。

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