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1
Should elective lymph node dissection be used for treatment of primary melanoma?选择性淋巴结清扫术是否应用于原发性黑色素瘤的治疗？
J Cancer Res Clin Oncol. 1989;115(5):470-3. doi: 10.1007/BF00393340.
2
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4
Elective lymph node dissection in patients with melanoma: systematic review and meta-analysis of randomized controlled trials.黑色素瘤患者的选择性淋巴结清扫术：随机对照试验的系统评价和荟萃分析
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Cost-effectiveness of using prognostic information to select women with breast cancer for adjuvant systemic therapy.利用预后信息为乳腺癌患者选择辅助性全身治疗的成本效益
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Role of elective lymph node dissection in stage I malignant melanoma: evaluation by matched pair analysis.
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[Elective lymph node dissection in primary malignant melanoma].
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本文引用的文献

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Efficacy of elective lymph node dissection in patients with intermediate thickness primary melanoma.选择性淋巴结清扫术对原发性中等厚度黑色素瘤患者的疗效。
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选择性淋巴结清扫术是否应用于原发性黑色素瘤的治疗？

Should elective lymph node dissection be used for treatment of primary melanoma?

作者信息

Biess B, Bröcker E B, Drepper H, Klein M, Lippold A, Peters A

机构信息

Fachklinik Hornheide, Münster.

出版信息

J Cancer Res Clin Oncol. 1989;115(5):470-3. doi: 10.1007/BF00393340.

DOI:10.1007/BF00393340
PMID:2808487
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12211677/
Abstract

A bicenter study compared survival probability in patients with malignant melanoma clinical stage I, treated by wide excision only or wide excision with elective lymph node dissection (ELND). ELND improved the survival only in men with primary tumors of 1.51-3.0 mm thickness. In female patients those without ELND showed a better survival. Thus, the total group of patients did not benefit from ELND, i.e. its value for the improvement of survival from malignant melanoma stage I could not be statistically proven.

摘要

一项双中心研究比较了仅接受广泛切除或接受选择性淋巴结清扫术（ELND）的广泛切除治疗的I期恶性黑色素瘤患者的生存概率。ELND仅在原发性肿瘤厚度为1.51 - 3.0毫米的男性患者中提高了生存率。在女性患者中，未接受ELND的患者生存率更高。因此，患者总体并未从ELND中获益，即其对提高I期恶性黑色素瘤生存率的价值无法得到统计学证明。