Holland A Maleah, Martin Jeffrey S, Mattson Christopher D, Lohse Keith R, Finn Peter R, Stager Joel M
Department of Kinesiology, Indiana University, Bloomington, IN, USA; Department of Kinesiology, Auburn University, Auburn, AL, USA; Department of Kinesiology and Health Sciences, Augusta University, Augusta, GA, USA.
Department of Kinesiology, Auburn University, Auburn, AL, USA; Department of Cell Biology and Physiology, Edward Via College of Osteopathic Medicine-Auburn Campus, Auburn, AL, USA.
J Am Soc Hypertens. 2017 Feb;11(2):92-100. doi: 10.1016/j.jash.2016.12.005. Epub 2016 Dec 22.
Our study examined the relationship between habitual high levels of vigorous physical activity on large and small artery compliance via radial artery pulse wave analysis. Eighty-three healthy men (n = 44) and women (n = 39), aged 18-78 years, were recruited as habitually less active (light-to-moderate exercise ≤3 times/wk) or habitually highly active (vigorous exercise ≥5 times/wk). A multivariate analysis of variance revealed a significant interaction of age and activity level; habitual vigorous activity was associated with greater compliance in large and small arteries in older adults (40-78 years) and younger adults (18-22 years). In the large and small arteries, we observed an age-associated decrease in arterial compliance (aged ≥ 40 years), though it appears to be less pronounced in the large artery among habitually highly active subjects. This study suggests that aging may be associated with declines in large and small artery compliance that can be attenuated by habitual vigorous activity.
我们的研究通过桡动脉脉搏波分析，探讨了习惯性高强度体力活动与大、小动脉顺应性之间的关系。招募了83名年龄在18 - 78岁之间的健康男性（n = 44）和女性（n = 39），分为习惯性低活动水平组（轻度至中度运动≤3次/周）和习惯性高活动水平组（剧烈运动≥5次/周）。多因素方差分析显示年龄与活动水平存在显著交互作用；习惯性剧烈活动与老年成年人（40 - 78岁）和年轻成年人（18 - 22岁）的大、小动脉更高的顺应性相关。在大、小动脉中，我们观察到动脉顺应性随年龄增长而下降（年龄≥40岁），不过在习惯性高活动水平的受试者中，大动脉的这种下降似乎不太明显。这项研究表明，衰老可能与大、小动脉顺应性下降有关，而习惯性剧烈活动可以减轻这种下降。
