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使用带有可变密度插入物的圆柱形3D阵列调试用于机器人放射外科手术的蒙特卡罗算法。

Commissioning Monte Carlo algorithm for robotic radiosurgery using cylindrical 3D-array with variable density inserts.

作者信息

Dechambre D, Baart V, Cucchiaro S, Ernst C, Jansen N, Berkovic P, Mievis C, Coucke P, Gulyban A

机构信息

Liege University Hospital, Liège, Belgium.

Liege University Hospital, Liège, Belgium.

出版信息

Phys Med. 2017 Jan;33:152-158. doi: 10.1016/j.ejmp.2017.01.005. Epub 2017 Jan 11.

Abstract

INTRODUCTION

To commission the Monte Carlo (MC) algorithm based model of CyberKnife robotic stereotactic system (CK) and evaluate the feasibility of patient specific QA using the ArcCHECK cylindrical 3D-array (AC) with Multiplug inserts (MP).

RESULTS

Four configurations were used for simple beam setup and two for patient QA, replacing water equivalent inserts by lung. For twelve collimators (5-60mm) in simple setup, mean (SD) differences between MC and RayTracing algorithm (RT) of the number of points failing the 3%/1mmgamma criteria were 1(1), 1(3), 1(2) and 1(2) for the four MP configurations. Tracking fiducials were placed within AC for patient QA. Single lung insert setup resulted in mean gamma-index 2%/2mm of 90.5% (range [74.3-95.9]) and 82.3% ([66.8-94.5]) for MC and RT respectively, while 93.5% ([86.8-98.2]) and 86.2% ([68.7-95.4]) in presence of largest inhomogeneities, showing significant differences (p<0.05).

DISCUSSION

After evaluating the potential effects, 1.12g/cc PMMA and 0.09g/cc lung material assignment showed the best results. Overall, MC-based model showed superior results compared to RT for simple and patient specific testing, using a 2%/2mm criteria. Results are comparable with other reported commissionings for flattening filter free (FFF) delivery. Further improvement of MC calculation might be challenging as Multiplan has limited material library.

CONCLUSIONS

The AC with Multiplug allowed for comprehensive commissioning of CyberKnife MC algorithm and is useful for patient specific QA for stereotactic body radiation therapy. MC calculation accuracy might be limited due to Multiplan's insufficient material library; still results are comparable with other reported commissioning measurements using FFF beams.

摘要

引言

委托开发基于蒙特卡罗(MC)算法的射波刀机器人立体定向系统(CK)模型,并评估使用带有多插头插入件(MP)的ArcCHECK圆柱形三维阵列(AC)进行患者特定质量保证(QA)的可行性。

结果

简单射束设置使用了四种配置,患者QA使用了两种配置,用肺组织替代水等效插入件。在简单设置中,对于12种准直器(5 - 60毫米),四种MP配置下,MC算法与光线追踪算法(RT)之间,未能通过3%/1毫米伽马标准的点数的平均(标准差)差异分别为1(1)、1(3)、1(2)和1(2)。在AC内放置跟踪基准点用于患者QA。单肺插入件设置下,MC算法和RT算法的平均伽马指数2%/2毫米分别为90.5%(范围[74.3 - 95.9])和82.3%([66.8 - 94.5]),而在存在最大不均匀性时分别为93.5%([86.8 - 98.2])和86.2%([68.7 - 95.4]),显示出显著差异(p<0.05)。

讨论

在评估潜在影响后,1.12克/立方厘米的聚甲基丙烯酸甲酯(PMMA)和0.09克/立方厘米的肺组织材料赋值显示出最佳结果。总体而言,基于MC的模型在简单测试和患者特定测试中,使用2%/2毫米标准时,与RT相比显示出更好的结果。结果与其他报道的无均整器(FFF)射束调试结果相当。由于Multiplan的材料库有限,进一步改进MC计算可能具有挑战性。

结论

带有多插头的AC允许对射波刀MC算法进行全面调试,并且对于立体定向体部放射治疗的患者特定QA很有用。由于Multiplan的材料库不足,MC计算精度可能有限;但结果仍与其他报道的使用FFF射束的调试测量结果相当。

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