Alizadeh Ardalan, Abdollahzadeh Hamid
a Department of Medicinal and Aromatic Plants, Estahban Branch , Islamic Azad University , Estahban , Iran.
b Young Researchers and Elites Club, Estahban Branch , Islamic Azad University , Estahban , Iran.
Nat Prod Res. 2017 Sep;31(17):2081-2084. doi: 10.1080/14786419.2016.1274890. Epub 2017 Jan 17.
Pycnocycla bashagardiana is a rare endemic and endangered species that has been used in folkloric medicine in Southern Iran. This study aimed to evaluate the essential oil constituents and antimicrobial activity of wild and cultivated p. bashagardiana. The aerial parts of wild and cultivated plants were collected from two provinces of Iran. The essential oil was isolated by hydrodistillation and analyzed by a combination of capillary GC and GC-MS. The main components in wild plants were myristicin (39.12%), (E)-β-ocimene (21.97%), sabinene (15.0%) and cis-iso-miristicin (2.67%) and in cultivated plants, (E)-β-ocimene (55.40%), myristicin (18.27%), (Z)-β-ocimene (12.47%) and cis-iso-miristicin (2.94%) were the main constituents in essential oil. The in vitro antimicrobial activity of the essential oil of P. bashagardiana were studied against Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli and Candida albicans for the first time. The results showed that the oil exhibited strong antimicrobial activity against all the tested pathogens.
巴沙加德环孔菌是一种珍稀的特有濒危物种，在伊朗南部被用于民间医学。本研究旨在评估野生和栽培的巴沙加德环孔菌的精油成分及抗菌活性。野生和栽培植物的地上部分从伊朗的两个省份采集。通过水蒸馏法分离精油，并结合毛细管气相色谱和气相色谱 - 质谱联用仪进行分析。野生植物精油的主要成分是肉豆蔻醚（39.12%）、（E）-β-罗勒烯（21.97%）、桧烯（15.0%）和顺式异肉豆蔻醚（2.67%），而栽培植物精油的主要成分是（E）-β-罗勒烯（55.40%）、肉豆蔻醚（18.27%）、（Z）-β-罗勒烯（12.47%）和顺式异肉豆蔻醚（2.94%）。首次研究了巴沙加德环孔菌精油对金黄色葡萄球菌、表皮葡萄球菌、大肠杆菌和白色念珠菌的体外抗菌活性。结果表明，该精油对所有测试病原体均表现出较强的抗菌活性。
