Chaudhry Mamoona, Ahmad Saeed, Rashid Hamad Bin, Ud Din Iftikhar
Department of Epidemiology and Public Health, University of Veterinary and Animal Sciences, Lahore, Pakistan.
Department of Clinical Medicine and Surgery, University of Veterinary and Animal Sciences, Lahore, Pakistan.
Am J Trop Med Hyg. 2017 Apr;96(4):899-902. doi: 10.4269/ajtmh.16-0608. Epub 2017 Jan 16.
AbstractSwat, a lush green valley of 1.3 million persons, remained under militant insurgency from 2007 to 2009, which damaged the health infrastructure. An outbreak of dengue fever (DF) was declared in the valley in 2013. To investigate this outbreak, we established active surveillance of national hospitals and private clinics, reviewed available clinical and laboratory records, and conducted entomological survey. From August to November 2013, 16,000 suspected patients with acute febrile illness were presented to health facilities. Among those, 9,036 were confirmed positive for DF by clinical manifestation and presence of nonstructural protein 1-soluble antigen. Of 9,036 patients, majority were men and aged 21-40. The epidemic peaked in September 2013 ( = 6,487). The attack rate was 7.18/1,000 populations. Among the confirmed case-patients, 36 deaths were reported, and proportion of mortality was 0.4%. Each year, increase in age was significantly associated with risk of complication due to DF leading to death ( < 0.001).
摘要斯瓦特是一个拥有130万人口的郁郁葱葱的绿色山谷,2007年至2009年期间一直处于激进叛乱状态,这损害了卫生基础设施。2013年该山谷宣布爆发登革热疫情。为调查此次疫情,我们对国立医院和私人诊所建立了主动监测,查阅了现有的临床和实验室记录,并进行了昆虫学调查。2013年8月至11月,16000名疑似急性发热疾病患者前往医疗机构就诊。其中,9036例通过临床表现和非结构蛋白1可溶性抗原的存在确诊为登革热阳性。在9036例患者中,大多数为男性,年龄在21至40岁之间。疫情在2013年9月达到高峰(=6487例)。发病率为7.18/1000人口。在确诊病例中,报告了36例死亡,死亡率为0.4%。每年,年龄增长与登革热导致死亡的并发症风险显著相关(<0.001)。