Yang Lin, Nan Hairong, Liang Jun, Chan Yin Hang, Chan Laam, Sum Rita Wing Man, Kwan Yee Mei, Zhou Feifei, Meng Huaiqing, Suen Lorna Kwai Ping
School of Nursing, The Hong Kong Polytechnic University, Hong Kong Special Administrative Region.
Faculty of Health and Social Sciences, The Hong Kong Polytechnic University, Hong Kong Special Administrative Region.
Vaccine. 2017 Feb 7;35(6):889-896. doi: 10.1016/j.vaccine.2017.01.004. Epub 2017 Jan 13.
People with diabetes are at a higher risk of influenza infections and severe complications. The vaccination of close contacts could offer indirect protection to people with diabetes; this is known as "herd immunity." The aim of this study is to investigate the vaccination rates of people with diabetes and their household contacts in Hong Kong.
Face-to-face interviews with 158 patients diagnosed with Type 2 diabetes and aged ⩾65years were conducted in clinics. Telephone interviews were then conducted with 281 adult household contacts.
Seasonal influenza vaccination rates were 54.5% and 27.4%, in people with diabetes and their contacts, respectively. The vaccination status of patients was not significantly associated with the vaccination of their household contacts (p=0.073). Among household contacts, children or the elderly, the partners or couples of patients, and those with more hours of daily contact, or with chronic conditions, were associated with higher vaccination rates. However, only age remained significant after adjusting for confounding factors in logistic regression models.
The low vaccination rates of people with diabetes and their close contacts highlight the need to promote vaccination in susceptible populations and to educate the public about herd immunity.
糖尿病患者感染流感及出现严重并发症的风险更高。对密切接触者进行疫苗接种可为糖尿病患者提供间接保护；这被称为“群体免疫”。本研究的目的是调查香港糖尿病患者及其家庭接触者的疫苗接种率。
在诊所对158名年龄≥65岁的2型糖尿病患者进行面对面访谈。随后对281名成年家庭接触者进行电话访谈。
糖尿病患者及其接触者的季节性流感疫苗接种率分别为54.5%和27.4%。患者的疫苗接种状况与其家庭接触者的疫苗接种情况无显著关联（p = 0.073）。在家庭接触者中，儿童或老年人、患者的伴侣或配偶以及每日接触时间较长或患有慢性病的人，其疫苗接种率较高。然而，在逻辑回归模型中调整混杂因素后，只有年龄仍具有显著性。
糖尿病患者及其密切接触者的低疫苗接种率凸显了在易感人群中推广疫苗接种以及向公众宣传群体免疫的必要性。
