Song Jibin, Niu Gang, Chen Xiaoyuan
Laboratory of Molecular Imaging and Nanomedicine (LOMIN), National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health , Bethesda, Maryland 20892, United States.
Bioconjug Chem. 2017 Jan 18;28(1):105-114. doi: 10.1021/acs.bioconjchem.6b00521. Epub 2016 Nov 18.
Plasmonic nanostructures with unique physical and biological properties have attracted increased attention for potential biomedical applications. Polymers grafted on metal nanoparticle surface can be used as assembly regulating molecules to guide nanoparticles organize into ordered or hierarchical structures in solution, within condensed phases, or at interfaces. In this Topical Review, we will highlight recent efforts on self-assembly of gold nanoparticles coated with polymer brushes. How and what kind of polymer graft can be used to adjust nanoparticle interactions, to dictate interparticle orientation, and to determine assembled nanostructures will be discussed. Furthermore, the Topical Review will shed light on the physicochemical properties, including self-assembly behavior and kinetics, tunable localized surface plasmon resonance effect, enhanced surface enhanced Raman scattering, and other optical and thermal properties. The potential of self-assembled nanostructures for applications in different fields, especially in biomedicine, will also be elaborated.
具有独特物理和生物学特性的等离子体纳米结构因其潜在的生物医学应用而受到越来越多的关注。接枝在金属纳米颗粒表面的聚合物可作为组装调节分子，引导纳米颗粒在溶液中、凝聚相内或界面处组织成有序或分级结构。在这篇专题综述中，我们将重点介绍聚合物刷包覆的金纳米颗粒自组装的最新研究进展。将讨论如何以及使用何种聚合物接枝来调节纳米颗粒间的相互作用、决定颗粒间的取向并确定组装的纳米结构。此外，本专题综述将阐明其物理化学性质，包括自组装行为和动力学、可调谐的局域表面等离子体共振效应、增强的表面增强拉曼散射以及其他光学和热学性质。还将阐述自组装纳米结构在不同领域，特别是生物医学领域的应用潜力。
