Fragoso Yara Dadalti, Adoni Tarso, Alves-Leon Soniza Vieira, Apostolos-Pereira Samira L, Arruda Walter Oleschko, Brooks Joseph B Bidin, Cal Henrique S Rodrigues, Damasceno Carlos A Albuquerque, Gama Paulo Diniz, Goncalves Marcus V Magno, Jesus Carlos A da Silva de, Machado Suzana C Nunes, Mansur Letícia Fezer, Matta Andre P da Cunha, Mendes Maria Fernanda, Morales Rogerio Rizo, Nobrega Adaucto Wanderley da, Parolin Monica K Fiuza, Peres Mario Pietro, Ribeiro Marlise de Castro, Ruocco Heloisa Helena, Scherpenhuijzen Simone, Siquinelli Fabio, Stoney Patrick N, Varela Daniel Lima, Eboni Audred Cristina Biondo, Spessotto Caroline Vieira, Rocha Elisa Teixeira da, Lacerda Pamela Emanuele
Universidade Metropolitana de Santos, Departamento de Neurologia, Santos SP, Brasil.
Hospital Sírio Libanes, Departamento de Neurologia, São Paulo, SP, Brasil.
Arq Neuropsiquiatr. 2017 Jan;75(1):3-8. doi: 10.1590/0004-282X20160173.
Vitamin D has taken center stage in research and treatment of multiple sclerosis (MS). The objective of the present study was to assess the serum vitamin D levels of a large population of patients with MS and controls living in a restricted tropical area.
Data from 535 patients with MS and 350 control subjects were obtained from 14 cities around the Tropic of Capricorn.
The mean serum 25-OH vitamin D level was 26.07 ± 10.27 ng/mL for the control subjects, and 28.03 ± 12.19 ng/mL for patients with MS. No correlation was observed between vitamin D levels and the disability of patients over the disease duration.
At least for the region around the Tropic of Capricorn, serum levels of vitamin D typically are within the range of 20 to 30 ng/mL for controls and patients with MS.
维生素D在多发性硬化症（MS）的研究和治疗中占据了核心地位。本研究的目的是评估生活在热带受限地区的大量MS患者和对照人群的血清维生素D水平。
从南回归线附近的14个城市获取了535例MS患者和350例对照者的数据。
对照者的血清25-羟基维生素D平均水平为26.07±10.27 ng/mL，MS患者为28.03±12.19 ng/mL。在疾病病程中，未观察到维生素D水平与患者残疾之间的相关性。
至少在南回归线附近地区，对照者和MS患者的血清维生素D水平通常在20至30 ng/mL范围内。
