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一名急性淋巴细胞白血病患儿身上的单个黑色溃疡。

A single black ulcer in a child with acute lymphocytic leukemia.

作者信息

Vestita Michelangelo, Filoni Angela, Santoro Nicola, Arcamone Gianpaolo, Bonamonte Domenico

机构信息

Centro Di Riferimento Oncologico Della Basilicata (IRCCS), Via Padre Pio, Italy.

University of Bari - Bari, Italy.

出版信息

An Bras Dermatol. 2016 Nov-Dec;91(6):815-816. doi: 10.1590/abd1806-4841.20164989.

DOI:10.1590/abd1806-4841.20164989
PMID:28099607
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5193196/
Abstract

Ecthyma gangrenosum is an uncommon dermatological manifestation characterized by round, indurated ulcers with a central necrotic black eschar and surrounding erythema. This report describes the case of a 5-year-old girl, affected by acute lymphocytic leukemia, presenting with a black eschar on her right thigh. Such lesions should always be correctly identified to avoid potentially fatal bacteraemia. Furthermore, because of its similar clinical presentation, cutaneous anthrax must be ruled out.

摘要

坏疽性脓皮病是一种罕见的皮肤病表现,其特征为圆形、硬结性溃疡,中央有坏死性黑色焦痂及周围红斑。本报告描述了一名5岁患急性淋巴细胞白血病的女孩,其右大腿出现黑色焦痂的病例。此类病变必须始终正确识别,以避免潜在致命的菌血症。此外,由于其临床表现相似,必须排除皮肤炭疽。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb1d/5193196/1b811464651e/abd-91-06-0815-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb1d/5193196/1b811464651e/abd-91-06-0815-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb1d/5193196/1b811464651e/abd-91-06-0815-g01.jpg

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本文引用的文献

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Eschar and neck lymphadenopathy caused by Francisella tularensis after a tick bite: a case report.蜱叮咬后由土拉弗朗西斯菌引起的焦痂与颈部淋巴结病:一例报告
J Med Case Rep. 2011 Mar 19;5:108. doi: 10.1186/1752-1947-5-108.
2
Long-term results of the Italian Association of Pediatric Hematology and Oncology (AIEOP) Studies 82, 87, 88, 91 and 95 for childhood acute lymphoblastic leukemia.意大利儿科血液学和肿瘤学会(AIEOP)研究 82、87、88、91 和 95 号方案治疗儿童急性淋巴细胞白血病的长期结果。
Leukemia. 2010 Feb;24(2):255-64. doi: 10.1038/leu.2009.250. Epub 2009 Dec 17.
3
Non-pseudomonal ecthyma gangrenosum present in diclofenac-induced agranulocytosis.
非假单胞菌性坏疽性脓皮病出现在双氯芬酸诱导的粒细胞缺乏症中。
Eur J Dermatol. 2008 May-Jun;18(3):350-1. doi: 10.1684/ejd.2008.0410. Epub 2008 May 13.
4
Ecthyma gangrenosum: a rare cutaneous manifestation caused by Pseudomonas aeruginosa without bacteremia in a leukemic patient.坏疽性脓皮病:一名白血病患者发生的由铜绿假单胞菌引起的罕见皮肤表现,无菌血症。
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Cutaneous anthrax in adults: a review of 25 cases in the eastern Anatolian region of Turkey.成人皮肤炭疽:土耳其东安纳托利亚地区25例病例回顾
Infection. 2003 Oct;31(5):327-30. doi: 10.1007/s15010-003-3169-3.
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Ecthyma gangrenosum without bacteraemia in a leukaemic patient.一名白血病患者出现无菌血症的坏疽性脓皮病。
Clin Exp Dermatol. 2001 Jul;26(5):395-7. doi: 10.1046/j.1365-2230.2001.00843.x.
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8
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