Blaney Davidson E N, van Caam A P M, van der Kraan P M
Radboudumc, Experimental Rheumatology, The Netherlands.
Radboudumc, Experimental Rheumatology, The Netherlands.
Osteoarthritis Cartilage. 2017 Feb;25(2):175-180. doi: 10.1016/j.joca.2016.09.024. Epub 2017 Jan 16.
This review highlights a selection of literature in the area of osteoarthritis biology published between the 2015 and 2016 Osteoarthritis Research Society International (OARSI) World Congress. Highlights were selected from a pubmed search covering cartilage, bone, inflammation and pain. A personal selection was made based, amongst other things, on topics presented during the 2015 conference. This covers circadian rhythm, TGF-β signaling, autophagy, SIRT6, exercise, lubricin, TLR's, pain and NGF. Furthermore, in this review we have made an effort to connect these seemingly distant topics into one scheme of connections between them, revealing a theoretical big picture underneath.
本综述重点介绍了2015年至2016年国际骨关节炎研究学会（OARSI）世界大会期间发表的骨关节炎生物学领域的部分文献。重点内容是从涵盖软骨、骨骼、炎症和疼痛的PubMed搜索中挑选出来的。除其他因素外，个人选择还基于2015年会议期间提出的主题。这涵盖了昼夜节律、转化生长因子-β信号传导、自噬、SIRT6、运动、润滑素、Toll样受体、疼痛和神经生长因子。此外，在本综述中，我们努力将这些看似不相关的主题联系成一个相互关联的方案，揭示其背后的理论全貌。
