睡眠是为了遗忘。
Sleep Is for Forgetting.
作者信息
Poe Gina R
机构信息
Department of Integrative Biology and Physiology, University of California, Los Angeles, Los Angeles, California 90095-7246
出版信息
J Neurosci. 2017 Jan 18;37(3):464-473. doi: 10.1523/JNEUROSCI.0820-16.2017.
Abstract
It is possible that one of the essential functions of sleep is to take out the garbage, as it were, erasing and "forgetting" information built up throughout the day that would clutter the synaptic network that defines us. It may also be that this cleanup function of sleep is a general principle of neuroscience, applicable to every creature with a nervous system.
摘要
可以说，睡眠的一项基本功能可能是清除“垃圾”，即清除并“遗忘”一整天积累下来的信息，这些信息会使界定我们自身的突触网络变得杂乱。也有可能睡眠的这种清理功能是神经科学的一个普遍原理，适用于每一个拥有神经系统的生物。
相似文献
1
Sleep Is for Forgetting.睡眠是为了遗忘。
J Neurosci. 2017 Jan 18;37(3):464-473. doi: 10.1523/JNEUROSCI.0820-16.2017.
2
Sleep to Remember.睡以求记。
J Neurosci. 2017 Jan 18;37(3):457-463. doi: 10.1523/JNEUROSCI.0297-16.2017.
3
Brain neural patterns and the memory function of sleep.大脑神经模式与睡眠的记忆功能。
Science. 2021 Oct 29;374(6567):560-564. doi: 10.1126/science.abi8370. Epub 2021 Oct 28.
4
How rhythms of the sleeping brain tune memory and synaptic plasticity.睡眠中大脑节律如何调节记忆和突触可塑性。
Sleep. 2019 Jul 8;42(7). doi: 10.1093/sleep/zsz095.
5
Competing Roles of Slow Oscillations and Delta Waves in Memory Consolidation versus Forgetting.慢波振荡和德尔塔波在记忆巩固与遗忘中的竞争作用。
Cell. 2019 Oct 3;179(2):514-526.e13. doi: 10.1016/j.cell.2019.08.040.
6
Schema-conformant memories are preferentially consolidated during REM sleep.符合模式的记忆在快速眼动睡眠期间优先得到巩固。
Neurobiol Learn Mem. 2015 Jul;122:41-50. doi: 10.1016/j.nlm.2015.02.011. Epub 2015 Mar 6.
7
Sleep before and after learning promotes the consolidation of both neutral and emotional information regardless of REM presence.学习前后的睡眠能够促进中性和情感信息的巩固，无论是否存在快速眼动睡眠。
Neurobiol Learn Mem. 2016 Sep;133:136-144. doi: 10.1016/j.nlm.2016.06.015. Epub 2016 Jun 16.
8
Overnight improvements in two REM sleep-sensitive tasks are associated with both REM and NREM sleep changes, sleep spindle features, and awakenings for dream recall.两项对快速眼动睡眠敏感的任务在夜间的改善与快速眼动睡眠和非快速眼动睡眠的变化、睡眠纺锤波特征以及因梦境回忆而觉醒有关。
Neurobiol Learn Mem. 2015 Jul;122:88-97. doi: 10.1016/j.nlm.2014.09.007. Epub 2014 Oct 5.
9
Neuronal Oscillations Indicate Sleep-dependent Changes in the Cortical Memory Trace.神经元振荡表明皮质记忆痕迹中与睡眠相关的变化。
J Cogn Neurosci. 2017 Apr;29(4):698-707. doi: 10.1162/jocn_a_01071. Epub 2016 Oct 28.
10
Brain stimulation during an afternoon nap boosts slow oscillatory activity and memory consolidation in older adults.午后小睡期间进行脑部刺激可增强老年人的慢波振荡活动和记忆巩固。
Neuroimage. 2016 Nov 15;142:311-323. doi: 10.1016/j.neuroimage.2016.06.057. Epub 2016 Jul 2.
引用本文的文献
1
Pre-sleep experiences shape neural activity and dream content in the sleeping brain.睡前经历塑造睡眠大脑中的神经活动和梦境内容。
iScience. 2025 Jul 1;28(8):113032. doi: 10.1016/j.isci.2025.113032. eCollection 2025 Aug 15.
2
Concurrent presentation of memory-related odors and sounds nullified sleep reactivation benefits.与记忆相关的气味和声音同时出现会抵消睡眠再激活的益处。
bioRxiv. 2025 Jul 31:2025.07.25.666857. doi: 10.1101/2025.07.25.666857.
3
REM refines and rescues memory representations: a new theory.快速眼动睡眠（REM）改善并挽救记忆表征：一种新理论。
Sleep Adv. 2025 Jan 22;6(1):zpaf004. doi: 10.1093/sleepadvances/zpaf004. eCollection 2025.
4
Both slow wave and rapid eye movement sleep contribute to emotional memory consolidation.慢波睡眠和快速眼动睡眠都有助于情绪记忆巩固。
Commun Biol. 2025 Mar 23;8(1):485. doi: 10.1038/s42003-025-07868-5.
5
Multi-region processing during sleep for memory and cognition.睡眠期间用于记忆和认知的多区域处理。
Proc Jpn Acad Ser B Phys Biol Sci. 2025;101(3):107-128. doi: 10.2183/pjab.101.008.
6
Memory engram stability and flexibility.记忆印痕的稳定性和灵活性。
Neuropsychopharmacology. 2024 Nov;50(1):285-293. doi: 10.1038/s41386-024-01979-z. Epub 2024 Sep 18.
7
On the basis of sex and sleep: the influence of the estrous cycle and sex on sleep-wake behavior.基于性别与睡眠：发情周期和性别对睡眠-觉醒行为的影响。
Front Neurosci. 2024 Aug 29;18:1426189. doi: 10.3389/fnins.2024.1426189. eCollection 2024.
8
The impact of the physical activity intervention on sleep in children and adolescents with neurodevelopmental disorders: a systematic review and meta-analysis.体育活动干预对神经发育障碍儿童和青少年睡眠的影响：一项系统综述和荟萃分析。
Front Neurol. 2024 Aug 13;15:1438786. doi: 10.3389/fneur.2024.1438786. eCollection 2024.
9
Coupling of Slow Oscillations in the Prefrontal and Motor Cortex Predicts Onset of Spindle Trains and Persistent Memory Reactivations.前额叶和运动皮层慢波的耦合预测纺锤波串和持续记忆再激活的开始。
J Neurosci. 2024 Oct 23;44(43):e0621242024. doi: 10.1523/JNEUROSCI.0621-24.2024.
10
Sensational Dreams: The Prevalence of Sensory Experiences in Dreaming.轰动性的梦境：梦境中感官体验的普遍性。
Brain Sci. 2024 May 24;14(6):533. doi: 10.3390/brainsci14060533.
本文引用的文献
1
L-DOPA Oppositely Regulates Synaptic Strength and Spine Morphology in D1 and D2 Striatal Projection Neurons in Dyskinesia.左旋多巴对异动症中D1和D2纹状体投射神经元的突触强度和棘突形态具有相反的调节作用。
Cereb Cortex. 2016 Oct 17;26(11):4253-4264. doi: 10.1093/cercor/bhw263.
2
Heart rate variability during sleep in children with autism spectrum disorder.自闭症谱系障碍儿童睡眠期间的心率变异性
Clin Auton Res. 2016 Dec;26(6):423-432. doi: 10.1007/s10286-016-0375-5. Epub 2016 Aug 4.
3
β-Adrenergic receptor signaling and modulation of long-term potentiation in the mammalian hippocampus.β-肾上腺素能受体信号传导与哺乳动物海马体中长期增强效应的调节
Learn Mem. 2015 Aug 18;22(9):461-71. doi: 10.1101/lm.031088.113. Print 2015 Sep.
4
Sleep in Autism Spectrum Disorders.自闭症谱系障碍中的睡眠问题
Curr Sleep Med Rep. 2015 Jun;1(2):131-140. doi: 10.1007/s40675-015-0012-1.
5
Sleep alterations following exposure to stress predict fear-associated memory impairments in a rodent model of PTSD.在创伤后应激障碍的啮齿动物模型中，暴露于应激后睡眠改变预示着与恐惧相关的记忆损伤。
Exp Brain Res. 2015 Aug;233(8):2335-46. doi: 10.1007/s00221-015-4302-0. Epub 2015 May 28.
6
Cued memory reactivation during slow-wave sleep promotes explicit knowledge of a motor sequence.慢波睡眠期间的线索性记忆再激活促进对运动序列的显性知识。
J Neurosci. 2014 Nov 26;34(48):15870-6. doi: 10.1523/JNEUROSCI.1011-14.2014.
7
The impact of diurnal sleep on the consolidation of a complex gross motor adaptation task.昼夜睡眠对复杂粗大运动适应任务巩固的影响。
J Sleep Res. 2015 Feb;24(1):100-9. doi: 10.1111/jsr.12207. Epub 2014 Sep 25.
8
Interaction of the ADRB2 gene polymorphism with childhood trauma in predicting adult symptoms of posttraumatic stress disorder.ADRB2 基因多态性与儿童期创伤相互作用，预测成年创伤后应激障碍症状。
JAMA Psychiatry. 2014 Oct;71(10):1174-82. doi: 10.1001/jamapsychiatry.2014.999.
9
Trauma exposure and sleep: using a rodent model to understand sleep function in PTSD.创伤暴露与睡眠：利用啮齿动物模型了解创伤后应激障碍中的睡眠功能。
Exp Brain Res. 2014 May;232(5):1575-84. doi: 10.1007/s00221-014-3890-4. Epub 2014 Mar 13.
10
Theta frequency activity during rapid eye movement (REM) sleep is greater in people with resilience versus PTSD.与创伤后应激障碍（PTSD）患者相比，具有心理韧性的人在快速眼动（REM）睡眠期间的θ波频率活动更强。
Exp Brain Res. 2014 May;232(5):1479-85. doi: 10.1007/s00221-014-3857-5. Epub 2014 Feb 15.
Zotero 插件