太赫兹辐射对大鼠神经胶质细胞影响的研究。
Investigation of terahertz radiation influence on rat glial cells.
作者信息
Borovkova Mariia, Serebriakova Maria, Fedorov Viacheslav, Sedykh Egor, Vaks Vladimir, Lichutin Alexander, Salnikova Alina, Khodzitsky Mikhail
机构信息
Terahertz Biomedicine Laboratory, Photonics and Optical Information Department, ITMO University, 49 Kronverksky Ave, St. Petersburg 197101, Russia.
Terahertz Biomedicine Laboratory, Photonics and Optical Information Department, ITMO University, 49 Kronverksky Ave, St. Petersburg 197101, Russia; Immunology Department, Institute of Experimental Medicine, 12 Acad. Pavlov Str., St. Petersburg 197376, Russia.
出版信息
Biomed Opt Express. 2016 Dec 14;8(1):273-280. doi: 10.1364/BOE.8.000273. eCollection 2017 Jan 1.
Abstract
We studied an influence of continuous terahertz (THz) radiation (0.12 - 0.18 THz, average power density of 3.2 mW/cm) on a rat glial cell line. A dose-dependent cytotoxic effect of THz radiation is demonstrated. After 1 minute of THz radiation exposure a relative number of apoptotic cells increased in 1.5 times, after 3 minutes it doubled. This result confirms the concept of biological hazard of intense THz radiation. Diagnostic applications of THz radiation can be restricted by the radiation power density and exposure time.
摘要
我们研究了连续太赫兹（THz）辐射（0.12 - 0.18 THz，平均功率密度为3.2 mW/cm²）对大鼠神经胶质细胞系的影响。结果表明太赫兹辐射具有剂量依赖性细胞毒性作用。在太赫兹辐射暴露1分钟后，凋亡细胞的相对数量增加了1.5倍，3分钟后增加了一倍。这一结果证实了强太赫兹辐射具有生物危害性的观点。太赫兹辐射的诊断应用可能会受到辐射功率密度和暴露时间的限制。
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