Ratcliffe R, Kiff R S, Kingston R D, Walsh S H, Jeacock J
J R Coll Surg Edinb. 1989 Jun;34(3):152-5.
Time to diagnosis from first symptoms has been assessed in 332 patients with colorectal cancer treated by the three general surgeons in Trafford Health Authority. When compared with other series, delay to diagnosis has been shortened, particular general practitioner and hospital delay. Fewer patients presented as emergencies and a greater proportion of patients had early-stage disease. There was no significant difference in delay times between Dukes' stage B and C patients but there was a significant difference in survival at 2 years between these two stages. Delay times for patients with risk factors, family histories or diverticular disease were not significantly different from times in patients without these factors.
对特拉福德卫生局的三位普通外科医生治疗的332例结直肠癌患者从出现首发症状到确诊的时间进行了评估。与其他系列研究相比,确诊延迟时间缩短了,尤其是全科医生和医院延误时间。以急诊就诊的患者减少,更多患者患有早期疾病。Dukes B期和C期患者的延迟时间没有显著差异,但这两个阶段患者的2年生存率存在显著差异。有危险因素、家族史或憩室病患者的延迟时间与无这些因素患者的延迟时间无显著差异。