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高毒力及候选疫苗株猪链球菌SC19的基因组序列草图

Draft Genome Sequence of Hypervirulent and Vaccine Candidate Streptococcus suis Strain SC19.

作者信息

Teng Lin, Dong Xingxing, Zhou Yang, Li Zhiwei, Deng Limei, Chen Huanchun, Wang Xiaohong, Li Jinquan

机构信息

College of Food Science and Technology, Key Laboratory of Environment Correlative Dietology, Huazhong Agricultural University, Wuhan, Hubei, People's Republic of China.

Department of Animal Sciences, University of Florida, Gainesville, Florida, USA.

出版信息

Genome Announc. 2017 Jan 19;5(3):e01484-16. doi: 10.1128/genomeA.01484-16.

DOI:10.1128/genomeA.01484-16
PMID:28104658
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5255919/
Abstract

Streptococcus suis, a zoonotic bacterium found primarily in pigs, has been recognized recently as an emerging pathogen of humans. Herein, we describe the genome of Streptococcus suis strain SC19, a hypervirulent and vaccine candidate strain isolated from a pig amid the 2005 outbreak in China.

摘要

猪链球菌是一种主要在猪身上发现的人畜共患病细菌,最近已被确认为一种新出现的人类病原体。在此,我们描述了猪链球菌SC19菌株的基因组,该菌株是从2005年中国疫情期间一头猪身上分离出的高毒力疫苗候选菌株。

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本文引用的文献

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Predominance of Streptococcus suis ST1 and ST7 in human cases in China, and detection of a novel sequence type, ST658.在中国的人类病例中猪链球菌ST1和ST7占主导地位,并检测到一种新的序列型ST658。
Virulence. 2017 Aug 18;8(6):1031-1035. doi: 10.1080/21505594.2016.1243193. Epub 2016 Sep 30.
2
The Role of Porcine Monocyte Derived Dendritic Cells (MoDC) in the Inflammation Storm Caused by Streptococcus suis Serotype 2 Infection.猪单核细胞衍生树突状细胞(MoDC)在2型猪链球菌感染引起的炎症风暴中的作用
PLoS One. 2016 Mar 14;11(3):e0151256. doi: 10.1371/journal.pone.0151256. eCollection 2016.
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RASTtk: a modular and extensible implementation of the RAST algorithm for building custom annotation pipelines and annotating batches of genomes.RASTtk:一种用于构建定制注释管道和批量注释基因组的RAST算法的模块化可扩展实现。
Sci Rep. 2015 Feb 10;5:8365. doi: 10.1038/srep08365.
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Streptococcus suis infection: an emerging/reemerging challenge of bacterial infectious diseases?猪链球菌感染:细菌性传染病一个新出现/再次出现的挑战?
Virulence. 2014 May 15;5(4):477-97. doi: 10.4161/viru.28595. Epub 2014 Mar 25.
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The SEED and the Rapid Annotation of microbial genomes using Subsystems Technology (RAST).SEED 与利用子系统技术进行快速微生物基因组注释(RAST)。
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