Jamt Ragnhild E G, Gjerde Hallvard, Normann Per T, Bogstrand Stig T
a Department of Forensic Sciences , Oslo University Hospital , Oslo , Norway.
b Institute of Clinical Medicine , University of Oslo , Oslo , Norway.
Traffic Inj Prev. 2017 Oct 3;18(7):681-687. doi: 10.1080/15389588.2017.1283027. Epub 2017 Jan 23.
The objective of this study was to determine the prevalence of alcohol and potentially impairing drugs among the general driving population in Finnmark and to compare the prevalence among Norwegian, Russian, and other foreign drivers by analyzing samples of oral fluid.
In collaboration with local police, drivers were selected for a voluntary and anonymous study using a multistage cluster sampling procedure (selection of roads, time intervals, and drivers within each interval) from September 2014 to October 2015. Age, gender, citizenship, time, and geographical site were recorded. Samples of oral fluid were collected using the Quantisal device. The samples were analyzed for alcohol with an enzymatic method and for 12 illicit drugs and 16 medicinal drugs and some metabolites using ultra-high-performance liquid chromatography with tandem mass spectrometry detection.
A total of 3,228 drivers were asked to participate in the study. The refusal rate was 6.2%. Of the 3,027 participants in the study, 111 (3.7%) were Russian and 204 (6.7%) had citizenship other than Norwegian or Russian. The total prevalence of psychoactive substances was 4.3%. Alcohol was detected in 0.3%, psychoactive medicinal drugs in 2.5%, and illicit drugs in 1.6% of the samples. The most commonly found substances were the sleeping agent zopiclone (1.1%), tetrahydrocannabinol (THC; 1.1%), and the analgesic agent codeine (0.6%). Illicit drugs were detected significantly more often in samples from drivers of citizenship other than Norwegian or Russian. The prevalence of alcohol was somewhat higher among Russian drivers but not statistically significant. There were large differences between age groups and genders concerning illicit drugs and psychoactive medicinal drugs; illicit drugs were more frequently in samples from young male drivers, whereas psychoactive medicinal drugs were more frequently in samples from elderly female drivers.
The total prevalence of alcohol and drugs among the general driving population in Finnmark was low and similar to previous Norwegian roadside surveys. Illicit drugs were detected significantly more often in samples from drivers with citizenship other than Russian and Norwegian and among young male drivers.
本研究的目的是确定芬马克普通驾驶人群中酒精和潜在影响驾驶能力药物的流行情况,并通过分析口腔液样本比较挪威、俄罗斯和其他外国驾驶员中的流行情况。
2014年9月至2015年10月期间,与当地警方合作,采用多阶段整群抽样程序(选择道路、时间间隔以及每个间隔内的驾驶员)选取驾驶员参与一项自愿且匿名的研究。记录年龄、性别、国籍、时间和地理位置。使用Quantisal装置收集口腔液样本。采用酶法分析样本中的酒精含量,使用超高效液相色谱-串联质谱检测法分析12种非法药物、16种药用药物及一些代谢物。
共有3228名驾驶员被邀请参与研究。拒绝率为6.2%。在3027名研究参与者中,111名(3.7%)为俄罗斯人,204名(6.7%)拥有挪威或俄罗斯以外的国籍。精神活性物质的总流行率为4.3%。在0.3%的样本中检测到酒精,2.5%的样本中检测到精神活性药用药物,1.6%的样本中检测到非法药物。最常检测到的物质是安眠药佐匹克隆(1.1%)、四氢大麻酚(THC;1.1%)和镇痛药可待因(0.6%)。在挪威或俄罗斯以外国籍驾驶员的样本中,非法药物的检测频率明显更高。俄罗斯驾驶员中酒精的流行率略高,但无统计学意义。在非法药物和精神活性药用药物方面,年龄组和性别之间存在很大差异;非法药物在年轻男性驾驶员的样本中更为常见,而精神活性药用药物在老年女性驾驶员的样本中更为常见。
芬马克普通驾驶人群中酒精和药物的总流行率较低,与挪威之前的路边调查结果相似。在俄罗斯和挪威以外国籍的驾驶员样本以及年轻男性驾驶员中,非法药物的检测频率明显更高。