Shang X, Scott D, Hodge A, Khan B, Khan N, English D R, Giles G G, Ebeling P R, Sanders K M
Xianwen Shang, Melbourne Medical School-Western Campus, Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne, Level 3, 176 Furlong Road, St Albans, Vic 3021, Australia. Tel: 61 (0)3 8395 8093, Fax: 61 (0)3 8395 8258, E-mail:
J Nutr Health Aging. 2017;21(2):147-151. doi: 10.1007/s12603-016-0738-6.
This study aimed to examine the association between baseline and changes in dietary quality assessed by the Alternative Healthy Eating Index-2010 (AHEI-2010) and abdominal aortic calcification (AAC) among community-dwelling older adults.
Population-based longitudinal study.
A subset of the Melbourne Collaborative Cohort Study (MCCS).
262 community-dwelling adults (60% female) aged 53 ± 5 years at baseline.
Dietary intake was assessed using validated Food Frequency Questionnaires at baseline (1990-1994) and follow-up (2010-2011). AAC was evaluated by radiography and dual-energy x-ray absorptiometry (DXA) at follow-up.
Higher baseline AHEI-2010 score was associated with lower AAC severity by radiography [OR (95% CI) for Tertile 3 VS Tertile 1: 0.53 (0.29-0.99)] after adjustment for gender, age, physical activity, smoking, BMI, systolic blood pressure, plasma total cholesterol, calcium and energy intake. The association between AHEI-2010 and AAC severity by DXA was also significant in the multivariate-adjusted model [OR (95% CI) for Tertile 3 VS Tertile 1: 0.38 (0.20-0.70)]. Changes in AHEI-2010 over 18 years were not associated with AAC severity.
Baseline but not the changes in AHEI-2010 was inversely associated with the risk of AAC severity suggesting that a high quality diet might help prevent or delay the progression of AAC in community-dwelling older adults and the benefits might be manifested over the long-term.
本研究旨在探讨采用2010年替代健康饮食指数（AHEI - 2010）评估的基线饮食质量及其变化与社区居住老年人腹主动脉钙化（AAC）之间的关联。
基于人群的纵向研究。
墨尔本协作队列研究（MCCS）的一个子集。
262名社区居住成年人，基线时年龄为53±5岁，女性占60%。
在基线（1990 - 1994年）和随访（2010 - 2011年）时，使用经过验证的食物频率问卷评估饮食摄入量。随访时通过X线摄影和双能X线吸收法（DXA）评估AAC。
在调整性别、年龄、身体活动、吸烟、体重指数、收缩压、血浆总胆固醇、钙和能量摄入后，较高的基线AHEI - 2010得分与X线摄影显示的较低AAC严重程度相关[第三三分位数与第一三分位数相比的OR（95%CI）：0.53（0.29 - 0.99）]。在多变量调整模型中，AHEI - 2010与DXA评估的AAC严重程度之间的关联也显著[第三三分位数与第一三分位数相比的OR（95%CI）：0.38（0.20 - 0.70）]。18年间AHEI - 2010的变化与AAC严重程度无关。
AHEI - 2010的基线水平而非其变化与AAC严重程度风险呈负相关，这表明高质量饮食可能有助于预防或延缓社区居住老年人AAC的进展，且这种益处可能在长期内显现。
