García-Lara J M A, Navarrete-Reyes A P, Medina-Méndez R, Aguilar-Navarro S G, Avila-Funes J A
José Alberto Ávila-Funes. Department of Geriatrics. Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán. Vasco de Quiroga 15. Colonia Belisario Domínguez Sección XVI. CP 14080; Tlalpan, Phone: + 52 (55) 54 87 09 00, 5703. E-mail:
J Nutr Health Aging. 2017;21(2):215-219. doi: 10.1007/s12603-016-0728-8.
To determine the socio-demographic and health factors associated with a biomedical phenotype of successful aging (SA) among Mexican community-dwelling elderly.
DESIGN, SETTING AND PARTICIPANTS: Cross-sectional study of 935 older adults aged 70 or older participating in the Mexican Study of Nutritional and Psychosocial Markers of Frailty.
SA was operationalized in accordance with the phenotype proposed by Rowe and Kahn. Univariate and multivariate logistic regression analyses were carried out in order to identify the correlates of SA.
The phenotype of SA was present in 10% of participants. Age (P < 0.001), illiteracy (P = 0.021), polypharmacy (P < 0.001), and physical pain (P < 0.001) were factors independently and inversely associated with the presence of the SA phenotype. The only variable positively associated with SA was good self-perceived health-status (P < 0.001).
Although age is not modifiable, several other factors associated with SA are. If we are to promote SA, efforts should be made towards improving those modifiable factors negatively associated with its presence, such as pain or polypharmacy. Also, enhancing factors positively associated to it might play a role in improving wellbeing.
确定墨西哥社区居住老年人中与成功老龄化(SA)生物医学表型相关的社会人口学和健康因素。
设计、背景与参与者:对935名70岁及以上参与墨西哥衰弱营养和心理社会标志物研究的老年人进行横断面研究。
SA按照Rowe和Kahn提出的表型进行操作化定义。进行单变量和多变量逻辑回归分析以确定SA的相关因素。
10%的参与者具有SA表型。年龄(P < 0.001)、文盲(P = 0.021)、多重用药(P < 0.001)和身体疼痛(P < 0.001)是与SA表型存在独立且呈负相关的因素。与SA呈正相关的唯一变量是良好的自我感知健康状况(P < 0.001)。
虽然年龄不可改变,但与SA相关的其他几个因素是可以改变的。如果我们要促进SA,应努力改善那些与其存在呈负相关的可改变因素,如疼痛或多重用药。此外,增强与其呈正相关的因素可能有助于改善幸福感。