葡萄膜炎的并发症：北加州葡萄膜炎的流行病学研究。
Complications of Uveitis: The Northern California Epidemiology of Uveitis Study.
机构信息
a Francis I. Proctor Foundation for Research in Ophthalmology, San Francisco, California, USA.
b University of California, San Francisco , Department of Ophthalmology, Koret Vision Research Center , San Francisco , California , USA.
出版信息
Ocul Immunol Inflamm. 2018;26(4):584-594. doi: 10.1080/09273948.2016.1247174. Epub 2017 Jan 23.
PURPOSE
To describe the uveitis complications in a large, community-based cohort.
METHODS
Retrospective, community-based, cross-sectional cohort study analyzing complications and associations with complications.
RESULTS
A total of 844 cases of uveitis were found; 342 were new-onset, and 462 were prior-onset. In total, 29.5% of patients were affected by one or more complications associated with age, gender, course, and anatomic location of uveitis. Visual loss was experienced by 19.1% of patients and was associated with age, course of disease, and anatomic location of uveitis. Of the patients who developed glaucoma or elevated intraocular pressure over 30 mmHg, 3.9% (n = 33) were related solely to uveitis; 5.2% (n = 44) had an unclear or combined mechanism; and 1.8% (n = 15) were related solely to steroid response. Cystoid macular edema was associated with course of disease and anatomic location of uveitis.
CONCLUSIONS
Complications affect a significant portion of uveitis patients, and are often associated with demographic and clinical factors.
目的
描述大型社区为基础的葡萄膜炎患者群体中的葡萄膜炎并发症。
方法
回顾性、社区为基础、横断面队列研究，分析并发症及与并发症的相关性。
结果
共发现 844 例葡萄膜炎患者；342 例为新发，462 例为既往发作。总共 29.5%的患者发生了一种或多种与年龄、性别、病程和葡萄膜炎解剖位置相关的并发症。19.1%的患者出现视力丧失，与年龄、病程和葡萄膜炎解剖位置有关。眼压升高或青光眼患者中，有 3.9%（n=33）仅与葡萄膜炎有关；5.2%（n=44）机制不明确或混合；1.8%（n=15）仅与类固醇反应有关。黄斑囊样水肿与病程和葡萄膜炎解剖位置有关。
结论
并发症影响了很大一部分葡萄膜炎患者，并且通常与人口统计学和临床因素相关。
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