Ishidate M, Odagiri Y
National Institute of Hygienic Sciences, Tokyo, Japan.
Mutat Res. 1989 Nov;224(3):357-9. doi: 10.1016/0165-1218(89)90179-1.
Male ICR/JCL mice were given a single intraperitoneal injection of 125, 250, and 500 mg/kg of caprolactam (CAP), or 250, 500, and 1000 mg/kg of benzoin (ZOIN). Bone marrow preparations were made 24, 30, and 48 h after treatment with the maximum dose, and 30 h after treatment with the other doses. The slides were coded before microscopic examination. No significant increase was found in the incidence of micronucleated polychromatic erythrocytes after treatment with either CAP or ZOIN.
对雄性ICR/JCL小鼠腹腔注射一次己内酰胺（CAP），剂量分别为125、250和500毫克/千克，或安息香（ZOIN），剂量分别为250、500和1000毫克/千克。在以最大剂量处理后24、30和48小时，以及以其他剂量处理后30小时制备骨髓标本。在显微镜检查前对玻片进行编码。用CAP或ZOIN处理后，微核多染红细胞的发生率均未发现显著增加。
