Kubota M, Nakamura T, Sunami K, Ozawa Y, Namba H, Yamaura A, Makino H
Department of Neurological Surgery, School of Medicine, Chiba University, Japan.
Neurosurg Rev. 1989;12 Suppl 1:393-9. doi: 10.1007/BF01790681.
The negative shift of DC potential was associated with an increase of extracellular potassium and energy metabolism. Therefore this dramatic phenomenon following the trauma to the brain was thought to be identical to spreading depression. 1. Spreading depression was most frequently observed between one and two hours after injury. 2. Spreading depression can be elicited in the deep structures as well as in the cortex. The more severe the injury, the more frequently the negative shifts were observed. The DC index seems to correlate well with the severity of the experimental model. It is concluded that the energy metabolism after the brain contusion was different from structure to structure and was changing continuously in the course of time.
直流电位的负向偏移与细胞外钾离子增加及能量代谢有关。因此，这种脑外伤后出现的显著现象被认为与扩散性抑制相同。1. 扩散性抑制最常出现在受伤后1至2小时之间。2. 扩散性抑制可在深部结构以及皮层中引发。损伤越严重，负向偏移出现得越频繁。直流指数似乎与实验模型的严重程度密切相关。结论是，脑挫伤后的能量代谢因结构不同而不同，且在时间过程中不断变化。
