Hadaś Edward, Derda Monika, Cholewiński Marcin
Department of Biology and Medical Parasitology, Poznan University of Medical Sciences, 10 Fredry Street, 61-701, Poznan, Poland.
Parasitol Res. 2017 Mar;116(3):997-1001. doi: 10.1007/s00436-017-5377-2. Epub 2017 Jan 26.
Eye diseases caused by amoebae from the genus Acanthamoeba are usually chronic and severe, and their treatment is prolonged and not very effective. The difficulties associated with therapy have led to attempts at finding alternative treatment methods. Particularly popular is searching for cures among drugs made of plants. However, no substances with total efficacy in treating Acanthamoeba keratitis have been identified.Results of our semi in vivo studies of tea tree oil simulating eyeball infection demonstrated 100% effectiveness in the case of both trophozoites and cysts of amoebae from the genus Acanthamoeba. The action of tea tree oil indicates that this is the first substance with a potential ability to quickly and effectively remove the amoebae from the eye. Tea tree oil has the ability to penetrate tissues, which allows it to destroy amoebae in both the shallow and deep layers of the cornea. The present research into the use of tea tree oil in the therapy of Acanthamoeba infection is the first study of this type in parasitology. It offers tremendous potential for effective treatment of Acanthamoeba keratitis and other diseases caused by these protozoa.
棘阿米巴属的阿米巴原虫引起的眼部疾病通常是慢性且严重的,其治疗过程漫长且效果不佳。与治疗相关的困难促使人们尝试寻找替代治疗方法。在植物制成的药物中寻找治疗方法尤其流行。然而,尚未发现对治疗棘阿米巴角膜炎有完全疗效的物质。我们对茶树油模拟眼球感染的半体内研究结果表明,对于棘阿米巴属的滋养体和包囊,茶树油的有效性均为100%。茶树油的作用表明,这是第一种具有快速有效清除眼部阿米巴原虫潜在能力的物质。茶树油具有穿透组织的能力,这使其能够在角膜的浅层和深层破坏阿米巴原虫。目前关于茶树油用于治疗棘阿米巴感染的研究是寄生虫学领域的首次此类研究。它为有效治疗棘阿米巴角膜炎及其他由这些原生动物引起的疾病提供了巨大潜力。