Klimova Blanka, Kuca Kamil
Department of Neurology, University Hospital Hradec Kralove, Hradec Kralove, Czech Republic.
Biomedical Research Centrum, University Hospital Hradec Kralove, Hradec Kralove, Rokitanskeho 62, 50003, Hradec Kralove, Czech Republic.
Curr Alzheimer Res. 2017;14(6):680-685. doi: 10.2174/1567205014666170117103656.
Alzheimer´s disease (AD) is a serious and complex neurodegenerative disease. Currently, there are about 44 million people suffering from AD all over the world and this number is expected to rapidly grow due to demographic changes. The disease can be treated both pharmacologically and non-pharmacologically. Unfortunately, it cannot be cured yet. Nevertheless, the drugs for the treatment of AD are quite expensive, have different side effects and only delay symptoms of this disease. Therefore researchers suggest the use of various non-pharmacological therapies. Apart from relatively popular in western world such as physical activities, cognitive training or healthy diet, Chinese medicine starts to be practiced in Europe.
The purpose of this mini-review is to discuss the concept of Chinese medicine and explore its most common and effective forms in the treatment of AD.
This was done by conducting a literature search in the world´s acknowledged databases such as Web of Science, Scopus, PubMed and Springer.
Five randomized controlled clinical trial studies were analyzed and their findings were discussed.
The authors of this mini-review list the key benefits (e.g., positive results of the reviewed randomized clinical trials studies for the improvement of cognitive decline in AD) and limitations (e.g., low awareness of benefits of TCM in Europe) of Chinese medicine therapy for the treatment of AD.
阿尔茨海默病（AD）是一种严重且复杂的神经退行性疾病。目前，全球约有4400万人患有AD，由于人口结构变化，这一数字预计将迅速增长。该疾病可通过药物和非药物方法进行治疗。不幸的是，它尚未能被治愈。然而，用于治疗AD的药物相当昂贵，有不同的副作用，且只能延缓该疾病的症状。因此，研究人员建议采用各种非药物疗法。除了在西方世界相对流行的如体育活动、认知训练或健康饮食外，中医药开始在欧洲得到应用。
本综述的目的是讨论中医药的概念，并探索其在治疗AD中最常见且有效的形式。
通过在世界公认的数据库如科学网、Scopus、PubMed和施普林格等进行文献检索来完成。
分析了五项随机对照临床试验研究，并讨论了其结果。
本综述的作者列出了中医药疗法治疗AD的主要益处（如所综述的随机临床试验研究对改善AD认知衰退的积极结果）和局限性（如欧洲对中医药益处的认知度较低）。
