Department of Neurology, University Hospital Hradec Kralove, Hradec Kralove, Czech Republic.
Department of Chemistry, Faculty of Science, University of Hradec Kralove, Hradec Kralove, Czech Republic.
J Alzheimers Dis. 2019;68(3):1185-1192. doi: 10.3233/JAD-181281.
Currently, there is an increase in the number of older people worldwide. Unfortunately, this demographic trend causes a rise in aging diseases, one of which is dementia. Recent research studies have indicated that mild cognitive impairment (MCI) may serve as a predictor of dementia in many patients. At present, there is no pharmacological treatment against MCI. Therefore, there is constant search for novel alternative non-pharmacological approaches to improve MCI. One of the effective complementary emerging approaches seems to be Traditional Chinese Medicine (TCM), which is nowadays becoming quite popular in the treatment of different disorders. The purpose of this study is to explore the efficacy of TCM as an effective complementary non-pharmacological tool for the improvement and treatment of MCI in older adults. The methods used for this review study included a literature search in the world's databases: Web of Science, Scopus, PubMed, and Springer. Afterwards, methods of comparison and evaluation of the findings from the selected studies were applied. The results of this review study indicate that TCM might be a beneficial complementary non-pharmacological approach to the improvement and treatment of MCI in older individuals. Nevertheless, more rigorously designed quality randomized clinical trials should be conducted in order to conclusively prove efficacy of TCM on the improvement of MCI among older population groups. In addition, there is an urgent call for a functional collaboration between western and eastern medicinal approaches, which could contribute to the enhancement of the overall quality of life of these aging population groups.
目前，全球老年人的数量正在增加。不幸的是，这一人口趋势导致了老年疾病的增加，其中之一是痴呆症。最近的研究表明，轻度认知障碍（MCI）可能是许多患者痴呆的预测因素。目前，针对 MCI 还没有药物治疗方法。因此，人们一直在不断寻找新的非药物替代方法来改善 MCI。一种有效的补充新兴方法似乎是中医药（TCM），它在治疗不同疾病方面正变得越来越流行。本研究的目的是探讨中医药作为改善和治疗老年人 MCI 的有效非药物补充工具的疗效。本综述研究采用的方法包括在世界数据库：Web of Science、Scopus、PubMed 和 Springer 中进行文献检索。然后，应用了比较和评估所选研究结果的方法。这项综述研究的结果表明，中医药可能是改善和治疗老年人 MCI 的有益的非药物补充方法。然而，应该进行更严格设计的高质量随机临床试验，以最终证明中医药在改善老年人群体的 MCI 方面的疗效。此外，迫切需要西方和东方医学方法之间的功能合作，这有助于提高这些老年人群体的整体生活质量。
