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内镜下鼻中隔成形术与传统鼻中隔成形术治疗鼻中隔偏曲的比较:随机临床试验的系统评价和荟萃分析

Endoscopic septoplasty versus conventional septoplasty for nasal septum deviation: a systematic review and meta-analysis of randomized clinical trials.

作者信息

Besharah Bayan O, Alharbi Hussain A, Abu Suliman Omar A, Althobaiti Hazem K, Mogharbel Ahmed M, Muathen Sumaiya H

机构信息

Department of Otolaryngology-Head and Neck Surgery, King Abdullah Medical Complex.

King Abdelaziz University, Rabigh Medical Collage, Saudi Arabia.

出版信息

Ann Med Surg (Lond). 2023 Jun 20;85(8):4015-4025. doi: 10.1097/MS9.0000000000000984. eCollection 2023 Aug.

DOI:10.1097/MS9.0000000000000984
PMID:37554910
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10406065/
Abstract

UNLABELLED

Although conventional septoplasty is widely used to treat nasal septum deviation, it increases morbidity due to poor visualization, poor illumination, the need for nasal packing, and difficulty in evaluating of the exact pathology. These drawbacks are also encountered in endoscopic septoplasty. Our study aimed to compare the treatment and complication outcomes of conventional and endoscopic septoplasty.

METHODS

The authors searched five electronic databases for relevant clinical trials. The records were screened for eligibility. Data were extracted from the included studies. Outcomes were pooled as risk ratios (RR) or mean differences with 95% CIs using RevMan ver.5.4.

RESULTS

Our study included 13 randomized clinical trials with 735 patients. Our analysis revealed that endoscopic septoplasty was significantly (<0.05) superior to conventional septoplasty for postoperative nasal obstruction relief, intraoperative and postoperative hemorrhage, and mucosal adhesion and synechiae across both long-term and short-term follow-ups. The following pooled RR values were found in short-term follow-up periods: [RR=1.20, 95% CI:=(1.09,1.32)]; [RR=0.27, 95% CI=(0.14,0.54)]; and [RR=0.16, 95% CI=(0.08,0.32)], respectively. Regarding persistent septal deviation and septal tear, endoscopic septoplasty had the upper hand only in short-term follow-up periods [RR=0.30, 95% CI=(0.17,0.53)] and [RR=0.26, 95% CI=(0.15,0.46)], respectively.

CONCLUSION

Our analysis revealed that endoscopic septoplasty was significantly superior to conventional septoplasty in postoperative nasal obstruction relief rate and reducing the risk of intraoperative and postoperative hemorrhage, mucosal adhesion and synechiae, persistent septal deviation, septal tear, and surgery duration.

摘要

未标注

尽管传统鼻中隔成形术被广泛用于治疗鼻中隔偏曲,但由于视野不佳、照明不足、需要鼻腔填塞以及难以评估确切病理情况,其发病率有所增加。内镜鼻中隔成形术也存在这些缺点。我们的研究旨在比较传统鼻中隔成形术和内镜鼻中隔成形术的治疗效果及并发症情况。

方法

作者检索了五个电子数据库以查找相关临床试验。对记录进行筛选以确定其是否符合条件。从纳入的研究中提取数据。使用RevMan 5.4软件将结果汇总为风险比(RR)或95%置信区间的均值差异。

结果

我们的研究纳入了13项随机临床试验,共735例患者。我们的分析表明,在内镜鼻中隔成形术在术后鼻塞缓解、术中和术后出血、黏膜粘连和瘢痕形成方面,无论长期还是短期随访,均显著(<0.05)优于传统鼻中隔成形术。在短期随访期内,得到以下汇总RR值:[RR = 1.20,95%置信区间:=(1.09, 1.32)];[RR = 0.27,95%置信区间=(0.14, 0.54)];以及[RR = 0.16,95%置信区间=(0.08, 0.32)],分别对应上述情况。关于持续性鼻中隔偏曲和鼻中隔撕裂,内镜鼻中隔成形术仅在短期随访期占优势,[RR = 0.30,95%置信区间=(0.17, 0.53)]和[RR = 0.26,95%置信区间=(0.15, 0.46)],分别对应这两种情况。

结论

我们的分析表明,内镜鼻中隔成形术在术后鼻塞缓解率、降低术中和术后出血风险、黏膜粘连和瘢痕形成、持续性鼻中隔偏曲、鼻中隔撕裂以及手术时长方面,显著优于传统鼻中隔成形术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb50/10406065/68cc36063918/ms9-85-4015-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb50/10406065/e300a8b20693/ms9-85-4015-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb50/10406065/5a933fb7d6eb/ms9-85-4015-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb50/10406065/3acecca7f52c/ms9-85-4015-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb50/10406065/00778542c994/ms9-85-4015-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb50/10406065/68cc36063918/ms9-85-4015-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb50/10406065/e300a8b20693/ms9-85-4015-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb50/10406065/5a933fb7d6eb/ms9-85-4015-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb50/10406065/3acecca7f52c/ms9-85-4015-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb50/10406065/00778542c994/ms9-85-4015-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb50/10406065/68cc36063918/ms9-85-4015-g005.jpg

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