处于临床精神病高风险个体的睡眠障碍。
Sleep disturbances in individuals at clinical high risk for psychosis.
作者信息
Poe Sarah-Lucy, Brucato Gary, Bruno Nicolina, Arndt Leigh Y, Ben-David Shelly, Gill Kelly E, Colibazzi Tiziano, Kantrowitz Joshua T, Corcoran Cheryl M, Girgis Ragy R
机构信息
Columbia University Medical Center, Department of Psychiatry, New York, NY, USA; The New York State Psychiatric Institute, New York, NY, USA.
Columbia University Medical Center, Department of Psychiatry, New York, NY, USA; The New York State Psychiatric Institute, New York, NY, USA.
出版信息
Psychiatry Res. 2017 Mar;249:240-243. doi: 10.1016/j.psychres.2016.12.029. Epub 2016 Dec 23.
Abstract
There has been recent interest in understanding the role that sleep disturbance plays in patients at Clinical High Risk for psychosis (CHR). We assessed sleep disturbance in 194 CHR patients and 66 healthy control subjects and their relationship to symptoms (positive, negative and general functioning). Patients experienced significantly more sleep disturbance than healthy control subjects and their sleep disturbance was related to greater positive and negative symptoms and worse overall functioning. Targeting sleep disturbance in CHR individuals may provide alternative means of treating the CHR syndrome.
摘要
最近，人们对了解睡眠障碍在临床高危精神病患者（CHR）中所起的作用产生了兴趣。我们评估了194名CHR患者和66名健康对照者的睡眠障碍情况，以及它们与症状（阳性、阴性和总体功能）之间的关系。患者的睡眠障碍明显多于健康对照者，且他们的睡眠障碍与更严重的阳性和阴性症状以及更差的整体功能有关。针对CHR个体的睡眠障碍可能提供治疗CHR综合征的替代方法。
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