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用两株反刍兽考德里氏体对蜱暴露的血清阴性和血清阳性小反刍动物进行攻毒后的免疫情况

Immunity of tick-exposed seronegative and seropositive small stock challenged with two stocks of Cowdria ruminantium.

作者信息

Du Plessis J L, Van Gas L

机构信息

Veterinary Research Institute, Onderstepoort.

出版信息

Onderstepoort J Vet Res. 1989 Sep;56(3):185-8.

PMID:2812702
Abstract

Nineteen per cent and 32% of serologically positive sheep and goats in heartwater endemic areas of the Republic of South Africa were susceptible to challenge with, respectively, the Ball 3 and Welgevonden stocks of Cowdria ruminantium. There was good correlation between the results of the indirect fluorescent antibody test and immunity, since without exception all the seronegative animals reacted when they were challenged. The fact that only 74% of the seropositive sheep and goats were immune to challenge can probably be ascribed to the poor cross-protection between stocks of C. ruminantium and not to false positive serological reactions.

摘要

在南非共和国心水病流行地区,血清学检测呈阳性的绵羊和山羊中,分别有19%和32%对反刍兽考德里氏体的Ball 3株和韦尔格温登株攻击敏感。间接荧光抗体试验结果与免疫力之间存在良好的相关性,因为所有血清学阴性的动物在受到攻击时无一例外都有反应。血清学阳性的绵羊和山羊中只有74%对攻击具有免疫力,这一事实可能归因于反刍兽考德里氏体不同毒株之间交叉保护作用较差,而不是血清学反应出现假阳性。

相似文献

1
Immunity of tick-exposed seronegative and seropositive small stock challenged with two stocks of Cowdria ruminantium.用两株反刍兽考德里氏体对蜱暴露的血清阴性和血清阳性小反刍动物进行攻毒后的免疫情况
Onderstepoort J Vet Res. 1989 Sep;56(3):185-8.
2
The heterogenicity of Cowdria ruminantium stocks: cross-immunity and serology in sheep and pathogenicity to mice.反刍动物埃立克体菌株的异质性:绵羊的交叉免疫和血清学以及对小鼠的致病性
Onderstepoort J Vet Res. 1989 Sep;56(3):195-201.
3
An attempt to improve the immunization of sheep against heart-water by using different combinations of 3 stocks of Cowdria ruminantium.尝试通过使用反刍兽考德里氏体3个毒株的不同组合来提高绵羊对心水病的免疫效果。
Onderstepoort J Vet Res. 1990 Sep;57(3):205-8.
4
Antigenic differences between stocks of Cowdria ruminantium.
Res Vet Sci. 1988 Mar;44(2):186-9.
5
Antigenic diversity of Cowdria ruminantium isolates determined by cross-immunity.通过交叉免疫确定的反刍动物考德里氏体分离株的抗原多样性。
Res Vet Sci. 1991 Jul;51(1):24-8. doi: 10.1016/0034-5288(91)90025-j.
6
The detection of antibodies to Cowdria ruminantium in serum and C. ruminantium antigen in Amblyomma hebraeum by an enzyme-linked immunosorbent assay.通过酶联免疫吸附测定法检测血清中反刍动物考德里氏体抗体以及希伯来花蜱中的反刍动物考德里氏体抗原。
Onderstepoort J Vet Res. 1986 Mar;53(1):39-41.
7
The immunization of calves against heartwater: subsequent immunity both in the absence and presence of natural tick challenge.犊牛针对心水病的免疫接种:在有无自然蜱虫叮咬挑战情况下的后续免疫力。
Onderstepoort J Vet Res. 1984 Sep;51(3):193-6.
8
Colostrum-derived antibodies to Cowdria ruminantium in the serum of calves and lambs.犊牛和羔羊血清中源自初乳的抗反刍兽考德里氏体抗体。
Onderstepoort J Vet Res. 1984 Dec;51(4):275-6.
9
Fluorescent antibody technique to detect Cowdria ruminantium in in vitro-cultured macrophages and buffy coats from cattle, sheep, and goats.用荧光抗体技术检测牛、羊和山羊体外培养的巨噬细胞及血沉棕黄层中的反刍兽立克次氏体。
Am J Vet Res. 1986 Jun;47(6):1253-7.
10
Observations on mouse-infective stocks of Cowdria ruminantium: attempts to demonstrate antigenic changes of the Kwanyanga stock in mice.反刍兽考德里氏体小鼠感染株的观察:在小鼠中证明夸扬加株抗原变化的尝试。
Res Vet Sci. 1986 Jul;41(1):98-101.

引用本文的文献

1
Reinfection with Anaplasma phagocytophilum in BALB/c mice and cross-protection between two sympatric isolates.BALB/c小鼠中嗜吞噬细胞无形体的再次感染及两种同域分离株之间的交叉保护作用
Infect Immun. 2004 Aug;72(8):4723-30. doi: 10.1128/IAI.72.8.4723-4730.2004.
2
Protective immunity to heartwater (Cowdria ruminantium infection) is acquired after vaccination with in vitro-attenuated rickettsiae.用体外减毒立克次氏体疫苗接种后可获得对心水病(反刍兽考德里氏体感染)的保护性免疫。
Infect Immun. 1991 Feb;59(2):729-31. doi: 10.1128/iai.59.2.729-731.1991.