Gao Huiqiao, Xiao Meizhu, Bai Huimin, Zhang Zhenyu
Department of Obstetrics and Gynecology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
Int J Gynecol Cancer. 2017 Mar;27(3):608-612. doi: 10.1097/IGC.0000000000000905.
The aim of this study was to evaluate the sexual function and quality of life (QOL) and identify their associated factors in survivors of endometrial cancer.
The participants in this study were survivors of endometrial cancer who visited the gynecological outpatient department for routine surveillance from June 2014 to May 2015. The QOL and sexual function were measured using the Functional Assessment of Cancer Therapy-General (FACT-G) and Female Sexual Function Index questionnaires. A score less than 26.55 was defined as female sexual dysfunction (FSD). Multivariate analysis and logistic regression were performed to identify the factors associated with QOL and sexual function.
A total of 118 women completed the questionnaires. The results revealed that 68.6% of the patients had FSD and that 55.9% of the patients never had sexual intercourse with their partners after surgery. Age, followed by time after surgery, radiotherapy, and consultation, was significantly correlated with FSD. The median score of the FACT-G was 86 (range, 41-108). Chemotherapy and marital status were found to significantly impair physical and social/family well-being, respectively (P < 0.05), and monthly income was identified as a factor that significantly affected the total FACT-G scores.
The risk factors associated with FSD and QOL need to be studied in greater detail. Prospective researches that evaluate the effects of clinical psychological intervention on sexual function may be needed in the future.
本研究旨在评估子宫内膜癌幸存者的性功能和生活质量（QOL），并确定其相关因素。
本研究的参与者为2014年6月至2015年5月到妇科门诊进行常规监测的子宫内膜癌幸存者。使用癌症治疗功能评估通用量表（FACT-G）和女性性功能指数问卷来测量生活质量和性功能。得分低于26.55被定义为女性性功能障碍（FSD）。进行多变量分析和逻辑回归以确定与生活质量和性功能相关的因素。
共有118名女性完成了问卷。结果显示，68.6%的患者存在FSD，55.9%的患者术后从未与伴侣发生过性行为。年龄，其次是术后时间、放疗和咨询，与FSD显著相关。FACT-G的中位数得分为86（范围为41 - 108）。化疗和婚姻状况分别被发现会显著损害身体和社会/家庭幸福感（P < 0.05），月收入被确定为显著影响FACT-G总分的一个因素。
与FSD和生活质量相关的危险因素需要更详细地研究。未来可能需要进行前瞻性研究来评估临床心理干预对性功能的影响。
