Division of Gynecology and Perinatology, University Medical Centre Maribor, 2000 Maribor, Slovenia.
Department of Obstetrics and Gynecology, Faculty of Medicine, University of Maribor, 2000 Maribor, Slovenia.
Curr Oncol. 2022 Jul 22;29(8):5213-5222. doi: 10.3390/curroncol29080414.
The overall survival of women with endometrial cancer is excellent after management. Different management strategies are associated with variable patient-reported outcomes (PROs). Evaluating PROs in the follow-up period can aid in better counseling and intervention for PRO improvement. This study aimed to evaluate the properties of the Slovenian translation of the EORTC QLQ-EN24 assessment scale. Women treated at the University Medical Centre Maribor, Slovenia, between January 2016 and December 2019 were invited to report their symptoms using the EORTC QLQ-EN24 questionnaire. Data were correlated with treatment modalities and clinical characteristics. The median age of participants in our study was 61 years old. PROs were not specific to therapy or clinical characteristics. Overall, women who more frequently reported gastrointestinal symptoms, muscular pain, or back pain also had statistically more frequently decreased levels of PROs in other assessed areas. Women who reported sexual or vaginal problems more often reported significantly poorer body images. Sexual activity within 4 weeks prior to completing the scale was reported by 39% of women. Sexual functioning assessments also showed important correlations between sexual interest, enjoyment, and activity. Individualized follow-ups addressing PROs should be offered to better address concerns and improve long-term outcomes in women with endometrial cancer.
子宫内膜癌女性经治疗后总体生存状况良好。不同的管理策略与不同的患者报告结局（PROs）相关。在随访期间评估 PRO 有助于更好地为改善 PRO 进行咨询和干预。本研究旨在评估斯洛文尼亚语版 EORTC QLQ-EN24 评估量表的特性。2016 年 1 月至 2019 年 12 月期间，在斯洛文尼亚马里博尔大学医学中心接受治疗的女性被邀请使用 EORTC QLQ-EN24 问卷报告其症状。数据与治疗方式和临床特征相关联。我们研究中的参与者的中位年龄为 61 岁。PROs 与治疗或临床特征无关。总体而言，经常报告胃肠道症状、肌肉疼痛或背痛的女性，在其他评估领域中，PROs 水平下降的频率也更高。经常报告性或阴道问题的女性，其身体形象明显更差。39%的女性在完成量表前 4 周内有过性行为。性功能评估还显示了性兴趣、享受和活动之间的重要相关性。应提供个体化的随访以解决 PRO 问题，从而改善子宫内膜癌女性的长期预后。
