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多参数心脏磁共振成像在心肌炎和全身性炎症性疾病中的临床应用

Clinical applications of multi-parametric CMR in myocarditis and systemic inflammatory diseases.

作者信息

Lagan Jakub, Schmitt Matthias, Miller Christopher A

机构信息

North West Heart Centre, University Hospital of South Manchester, Manchester, UK.

Institute of Cardiovascular Sciences, Faculty of Medical & Human Sciences, University of Manchester, Manchester, M13 9NT, UK.

出版信息

Int J Cardiovasc Imaging. 2018 Jan;34(1):35-54. doi: 10.1007/s10554-017-1063-9. Epub 2017 Jan 27.

Abstract

Cardiac magnetic resonance (CMR) has changed the management of suspected viral myocarditis by providing a 'positive' diagnostic test and has lead to new insights into myocardial involvement in systemic inflammatory conditions. In this review we analyse the use of CMR tissue characterisation techniques across the available studies including T2 weighted imaging, early gadolinium enhancement, late gadolinium enhancement, Lake Louise Criteria, T2 mapping, T1 mapping and extracellular volume assessment. We also discuss the use of multiparametric CMR in acute cardiac transplant rejection and a variety of inflammatory conditions such as sarcoidosis, systemic lupus erythrematous, rheumatoid arthritis and systemic sclerosis.

摘要

心脏磁共振成像(CMR)通过提供一种“阳性”诊断测试,改变了疑似病毒性心肌炎的管理方式,并为全身性炎症性疾病中心肌受累情况带来了新的见解。在本综述中,我们分析了现有研究中CMR组织特征分析技术的应用,包括T2加权成像、钆剂早期强化、钆剂延迟强化、路易斯湖标准、T2映射、T1映射和细胞外容积评估。我们还讨论了多参数CMR在急性心脏移植排斥反应以及多种炎症性疾病(如结节病、系统性红斑狼疮、类风湿关节炎和系统性硬化症)中的应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2199/5797564/c74e3624b9e1/10554_2017_1063_Fig1_HTML.jpg

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