Crowson Aaron D, Colligan Robert C, Matteson Eric L, Davis John M, Crowson Cynthia S
From the Department of Health Sciences Research, the Department of Psychiatry and Psychology, and the Division of Rheumatology, Department of Medicine, the Mayo Clinic, Rochester, Minnesota, USA.
A.D. Crowson, BA, Department of Health Sciences Research, Mayo Clinic; R.C. Colligan, PhD, Department of Psychiatry and Psychology, Mayo Clinic; E.L. Matteson, MD, MPH, Department of Health Sciences Research, and Division of Rheumatology, Department of Medicine, Mayo Clinic; J.M. Davis III, MD, MS, Division of Rheumatology, Department of Medicine, Mayo Clinic; C.S. Crowson, MS, Department of Health Sciences Research, and Division of Rheumatology, Department of Medicine, Mayo Clinic.
J Rheumatol. 2017 Feb;44(2):170-173. doi: 10.3899/jrheum.160026. Epub 2016 Nov 15.
To determine whether pessimistic explanatory style altered the risk for and mortality of patients with rheumatoid arthritis (RA).
The study included subjects from a population-based cohort with incident RA and a non-RA comparison cohort who completed the Minnesota Multiphasic Personality Inventory.
Among 148 RA and 135 non-RA subjects, pessimism was associated with development of rheumatoid factor (RF)-positive RA. Pessimism was associated with an increased risk of mortality [HR 2.88 with similar magnitude to RF+ (HR 2.28)].
Pessimistic explanatory style was associated with an increased risk of developing RA and increased mortality rate in patients with RA.
确定悲观解释风格是否会改变类风湿关节炎（RA）患者的患病风险和死亡率。
该研究纳入了来自基于人群的队列中患新发RA的受试者以及一个非RA对照队列，这些受试者均完成了明尼苏达多相人格调查表。
在148名RA受试者和135名非RA受试者中，悲观情绪与类风湿因子（RF）阳性RA的发生有关。悲观情绪与死亡风险增加相关[风险比（HR）为2.88，与RF阳性（HR为2.28）的幅度相似]。
悲观解释风格与RA发病风险增加及RA患者死亡率升高相关。
