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艾滋病毒/艾滋病患者的临床流行病学分析

Clinico-Epidemiological Analysis of HIV/AIDS Patients.

作者信息

Ertunc Baris, Kaya Selcuk, Koksal Iftihar

机构信息

Department of Infectious Diseases and Clinical Microbiology, Karadeniz Technical University School of Medicine, Trabzon, Turkey.

出版信息

Eurasian J Med. 2016 Oct;48(3):157-161. doi: 10.5152/eurasianjmed.2016.15203.

Abstract

OBJECTIVE

The aim of this study was to examine clinico-epidemiological properties of HIV/AIDS patients.

MATERIALS AND METHODS

For this purpose, 115 HIV/AIDS patients monitored in our clinic between January 1, 1998, and December 31, 2013, were retrospectively evaluated.

RESULTS

For the 115 patients with a diagnosis of HIV/AIDS that we monitored, the mean age at the time of presentation was 34.5±13.21 (10-79) years. Eighty-nine (76.5%) patients were male and 27 (23.5%), female. In this study, HIV/AIDS was the most prevalent in the young male population with a low educational and sociocultural level. The most common mode of transmission in our patients was heterosexual relations: approximately 1 patient in 3 had a history of traveling to countries with a high prevalence of HIV/AIDS, namely, Russia and Ukraine. The examination of diagnosis with respect to years showed an increase in new cases since 2008. Only 21 (18.3%) of our patients were diagnosed through clinical symptoms, while 91 (81.7%) during routine scanning. At first presentation, 68% of our patients were stage A; 4.7%, stage B; and 27.3%, stage C. The mean length of the monitoring of our patients was 2.74 years (2-180 months). Thirteen (11.3%) patients died due to opportunistic infections and malignities. The most common opportunistic infection was tuberculosis (16.5%), followed by syphilis and HBV. Malignity, most commonly intracranial tumor, was seen in 8.6% patients.

CONCLUSION

The disease was generally seen in the young male population with a low sociocultural level, and it was most frequently transmitted by heterosexual sexual contact. This clearly shows the importance of sufficient, accurate information, and education on the subject of the disease and its prevention. The fact that many of our patients were diagnosed in the late stage due to stigma and that diagnosis was largely made through scanning tests confirms the importance of these tests in early diagnosis.

摘要

目的

本研究旨在探讨人类免疫缺陷病毒/获得性免疫缺陷综合征(HIV/AIDS)患者的临床流行病学特征。

材料与方法

为此,对1998年1月1日至2013年12月31日期间在我院门诊接受监测的115例HIV/AIDS患者进行回顾性评估。

结果

在我们监测的115例诊断为HIV/AIDS的患者中,就诊时的平均年龄为34.5±13.21(10 - 79)岁。89例(76.5%)为男性,27例(23.5%)为女性。在本研究中,HIV/AIDS在教育和社会文化水平较低的年轻男性人群中最为普遍。我们的患者中最常见的传播方式是异性关系:约三分之一的患者有前往HIV/AIDS高发国家(即俄罗斯和乌克兰)旅行的历史。按年份进行诊断检查显示,自2008年以来新病例有所增加。我们的患者中只有21例(18.3%)通过临床症状确诊,而91例(81.7%)是在常规筛查中确诊。初诊时,68%的患者为A期;4.7%为B期;27.3%为C期。我们患者的平均监测时长为2.74年(2 - 180个月)。13例(11.3%)患者死于机会性感染和恶性肿瘤。最常见的机会性感染是结核病(16.5%),其次是梅毒和乙肝。恶性肿瘤,最常见的是颅内肿瘤,见于8.6%的患者。

结论

该疾病通常见于社会文化水平较低的年轻男性人群,最常见的传播途径是异性性接触。这清楚地表明了关于该疾病及其预防的充分、准确信息和教育的重要性。我们的许多患者因耻辱感而在晚期才被诊断出来,且很大程度上是通过筛查检查确诊的,这证实了这些检查在早期诊断中的重要性。

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