Poggio Claudio, Gulino Chiara, Mirando Maria, Colombo Marco, Pietrocola Giampiero
Department of Clinical-Surgical, Diagnostic and Pediatric Sciences, Section of Dentistry, University of Pavia, Pavia, Italy.
Department of Molecular Medicine, Unit of Biochemistry, University of Pavia, Pavia, Italy.
J Clin Exp Dent. 2017 Jan 1;9(1):e7-e12. doi: 10.4317/jced.53129. eCollection 2017 Jan.
The purpose of this study was to evaluate the preventive effects of different protective agents on dentine erosion, measuring mean percentage weight loss. Dissolution of dentine under erosive challenges caused by soft drinks was analyzed: specimens were weighed following each immersion period, with mean percent weight losses calculated.
Extracted teeth were sectioned into uniform slabs. Seventy permanent enamel specimens were randomly distributed to seven groups. Initial weights of all dentin specimens were performed. The fluoride pastes Remin Pro, MI Paste Plus, Tooth Mousse, Biorepair, Biorepair Plus and Regenerate were used in this study. A control group was treated just with tap water. The specimens then were immersed in Coca-Cola for a total of 32 min at room temperature. Finally each specimen was dry and weighed. The mass loss was calculated as a percentage of that observed prior the fluoride pastes application. Weight loss data were subjected to Analysis of Variance (One-way ANOVA) followed by Bonferroni's post hoc tests.
Percent weight loss of specimens exposed to early stages in Coca-Cola showed linear progression with time. Specimen's application of fluoridated varnishes such as Biorepair or Regenerate, prior immersion in Coca-Cola, significantly protect dentin from demineralization. Otherwise, application of Tooth Mousse or Biorepair Plus increased dentin demineralization starting from 24 min of immersion in Coca-Cola.
Despite the limitations of this study, the protective pastes that showed the less weight loss due to the acidic challenge are Biorepair and Regenerate. Dentine, erosion, protective agents, soft drinks, toothpastes.
本研究旨在通过测量平均失重百分比来评估不同保护剂对牙本质侵蚀的预防效果。分析了软饮料引起的侵蚀性挑战下牙本质的溶解情况：在每个浸泡期后对标本进行称重，并计算平均失重百分比。
将拔除的牙齿切成均匀的薄片。70个恒牙釉质标本随机分为7组。对所有牙本质标本进行初始称重。本研究使用了含氟牙膏Remin Pro、MI Paste Plus、Tooth Mousse、Biorepair、Biorepair Plus和Regenerate。对照组仅用自来水处理。然后将标本在室温下浸入可口可乐中总共32分钟。最后将每个标本干燥并称重。质量损失计算为使用含氟牙膏之前观察到的质量损失的百分比。对失重数据进行方差分析（单因素方差分析），然后进行Bonferroni事后检验。
暴露于可口可乐早期阶段的标本失重百分比随时间呈线性变化。在浸入可口可乐之前使用Biorepair或Regenerate等含氟清漆可显著保护牙本质免脱矿。否则，从浸入可口可乐24分钟开始，使用Tooth Mousse或Biorepair Plus会增加牙本质脱矿。
尽管本研究存在局限性，但因酸性挑战导致失重最少的保护膏是Biorepair和Regenerate。牙本质、侵蚀、保护剂、软饮料、牙膏。
