Caudal Victor, Snead Elisabeth C, Starrak Gregory S, Sathya Suresh, Feng Cindy X
Department of Small Animal Clinical Sciences (Caudal, Snead, Starrak, Sathya) and Statistics (Feng), Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4.
Can J Vet Res. 2017 Jan;81(1):53-58.
The objective of this study was to determine the feasibility of trephination of the frontal sinus and injection of antifungal cream using a medical bone marrow drill in dogs. Results were compared with frontal sinus trephination using a standard surgical technique. Bilateral trephination of the frontal sinuses was carried out in the heads of 11 cadavers using a medical bone marrow drill and a surgical bone chuck. The time taken to carry out the procedure using both techniques was compared. Before and after injection of antifungal cream into the frontal sinuses, computed-tomography (CT) scanning was done to assess for iatrogenic trauma and to determine the degree to which the sinuses were filled with each technique and evaluate the diffusion of the cream into the nasal cavity of each dog. The mean volume of the sinuses was 8.8 mL (3.1 to 14.3 mL). Trephination, flushing, and injecting of antifungal cream were significantly faster using the medical technique. There was no significant difference in the mean filling of the frontal sinuses between the medical (82.7%) and the surgical (82.4%) technique (-value = 0.3). Filling of the nasal cavity was classified as very good in 6/11 cases, with evidence of trauma caused by the surgical trephination technique in 1 head. Findings suggest that use of the medical bone marrow drill is highly feasible for frontal sinus trephination. Injection of antifungal cream into the frontal sinuses using the bone marrow needle resulted in good diffusion into the ipsilateral nasal cavity and could be used to treat aspergillosis when debridement or sinusoscopy is not deemed necessary.
本研究的目的是确定使用医用骨髓钻在犬类中进行额窦环钻术并注射抗真菌乳膏的可行性。将结果与使用标准手术技术进行的额窦环钻术进行比较。使用医用骨髓钻和手术用骨夹在11具尸体头部进行双侧额窦环钻术。比较了使用两种技术进行该操作所需的时间。在向额窦注射抗真菌乳膏前后,进行计算机断层扫描(CT)以评估医源性创伤,并确定每种技术填充鼻窦的程度,以及评估乳膏在每只犬鼻腔中的扩散情况。鼻窦的平均体积为8.8毫升(3.1至14.3毫升)。使用医用技术进行环钻、冲洗和注射抗真菌乳膏的速度明显更快。医用技术(82.7%)和手术技术(82.4%)在额窦平均填充率上无显著差异(P值 = 0.3)。11例中有6例鼻腔填充情况被评为非常好,1例头部有手术环钻技术造成创伤的迹象。研究结果表明,使用医用骨髓钻进行额窦环钻术具有高度可行性。使用骨髓针向额窦注射抗真菌乳膏可使其在同侧鼻腔中良好扩散,在清创或鼻窦镜检查不必要时可用于治疗曲霉病。